Display options
Cite
Wang GJ, Guo LY, Wang HX, et al. IP3R and RyR calcium channels are involved in neonatal rat cardiac myocyte hypertrophy induced by tumor necrosis factor-α. Am J Transl Res. 2017;9(2):343-354
Wang, G. J., Guo, L. Y., Wang, H. X., & Yao, Y. S. (2017). IP3R and RyR calcium channels are involved in neonatal rat cardiac myocyte hypertrophy induced by tumor necrosis factor-α. American journal of translational research, 9(2), 343-354.
Wang, Gui-Jun, et al. "IP3R and RyR calcium channels are involved in neonatal rat cardiac myocyte hypertrophy induced by tumor necrosis factor-α." American journal of translational research vol. 9,2 (2017): 343-354.
Wang GJ, Guo LY, Wang HX, Yao YS. IP3R and RyR calcium channels are involved in neonatal rat cardiac myocyte hypertrophy induced by tumor necrosis factor-α. Am J Transl Res. 2017 Feb 15;9(2):343-354. eCollection 2017. PMID: 28337264; PMCID: PMC5340671.
Copy Download .nbib Format: NLM
Share it on

Am J Transl Res. 2017 Feb 15;9(2):343-354. eCollection 2017.

IP3R and RyR calcium channels are involved in neonatal rat cardiac myocyte hypertrophy induced by tumor necrosis factor-α.

American journal of translational research

Gui-Jun Wang, Lian-Yi Guo, Hong-Xin Wang, Yu-Sheng Yao

Affiliations

  1. The First Affiliated Hospital, Jinzhou Medical University Jinzhou 121000, Liaoning, China.
  2. Department of Pharmacology, Jinzhou Medical University Jinzhou 121000, Liaoning, China.
  3. The Third Affiliated Hospital, Jinzhou Medical University Jinzhou 121000, Liaoning, China.

PMID: 28337264 PMCID: PMC5340671

Abstract

To investigate which calcium channels are involved in cardiac myocyte hypertrophy induced by TNF-α, cultured cardiomyocytes were treated with 100 μg/L TNF-α. In addition, three different calcium channel blockers (2-APB, ryanodine and nifedipine) were used, and the effects of each calcium channel blocker on cardiac hypertrophy induced by TNF-α were carefully observed. Measurements included cytosolic calcium transients ([Ca

Keywords: 4; 5-triphosphate receptor (IP3R); Cardiac myocyte hypertrophy; calcium; calcium channel; inositol 1; ryanodine receptor (RyR); tumor necrosis factor-α

References

  1. Br J Pharmacol. 2001 Jan;132(1):159-64 - PubMed
  2. Circ Res. 1985 Jun;56(6):884-94 - PubMed
  3. Nat Med. 2000 Nov;6(11):1221-7 - PubMed
  4. J Clin Invest. 1996 Dec 15;98(12):2854-65 - PubMed
  5. Circ Res. 1993 Sep;73(3):413-23 - PubMed
  6. J Card Fail. 2002 Dec;8(6 Suppl):S379-86 - PubMed
  7. Am J Physiol Cell Physiol. 2002 Jun;282(6):C1339-47 - PubMed
  8. Science. 1985 Nov 8;230(4726):630-2 - PubMed
  9. Eur J Pharmacol. 1996 Jul 4;307(3):323-9 - PubMed
  10. Circ Res. 2002 May 3;90(8):850-7 - PubMed
  11. J Biol Chem. 2007 Dec 7;282(49):35564-73 - PubMed
  12. Proc Natl Acad Sci U S A. 1989 Sep;86(17):6753-7 - PubMed
  13. Proc Natl Acad Sci U S A. 1975 Sep;72(9):3666-70 - PubMed
  14. J Clin Invest. 1993 Nov;92(5):2303-12 - PubMed
  15. Basic Res Cardiol. 2011 Nov;106(6):1193-205 - PubMed
  16. JCI Insight. 2016 Apr 21;1(5):null - PubMed
  17. Wiley Interdiscip Rev Syst Biol Med. 2016 Jan-Feb;8(1):37-67 - PubMed
  18. J Biol Chem. 1951 Nov;193(1):265-75 - PubMed
  19. Circulation. 1998 Apr 14;97(14 ):1382-91 - PubMed
  20. Am J Transl Res. 2016 Feb 15;8(2):778-98 - PubMed
  21. Eur J Pharmacol. 1999 Jul 2;376(1-2):139-48 - PubMed
  22. Circulation. 1997 Mar 4;95(5):1247-52 - PubMed
  23. Clin Exp Pharmacol Physiol. 2012 May;39(5):477-84 - PubMed
  24. Diabetes Metab Res Rev. 2007 Jul;23(5):356-67 - PubMed

Publication Types