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Br J Clin Pharmacol. 2017 Jul;83(7):1365-1368. doi: 10.1111/bcp.13281. Epub 2017 Apr 06.

When less is more - efficacy with less toxicity at the ED50.

British journal of clinical pharmacology

Simon Dimmitt, Hans Stampfer, Jennifer H Martin

Affiliations

  1. School of Medicine & Pharmacology, University of Western Australia, 3/10 McCourt St, West Leederville, 6007, Australia.
  2. Australian Community & Health Foundation, West Leederville, 6007, Australia.
  3. Joondalup Health Campus, The University of Western Australia, Crawley, WA, 6009, Australia.
  4. Consultant Psychiatrist, Sir Charles Gairdner Hospital, Perth, WA, Australia.
  5. University of Newcastle School of Medicine and Public Health, Callaghan, New South Wales, 2298, Australia.
  6. Department of Medicine, Hunter New England Local Health District, Newcastle, Australia.

PMID: 28387051 PMCID: PMC5465328 DOI: 10.1111/bcp.13281

[No abstract available.]

Keywords: dose-response; effective dose 50; pharmaceutical marketing

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