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Bioinformatics. 2017 May 01;33(9):1421-1423. doi: 10.1093/bioinformatics/btw838.

DistributedFBA.jl: high-level, high-performance flux balance analysis in Julia.

Bioinformatics (Oxford, England)

Laurent Heirendt, Ines Thiele, Ronan M T Fleming

Affiliations

  1. University of Luxembourg, Luxembourg Centre for Systems Biomedicine, Esch-sur-Alzette, Luxembourg.

PMID: 28453682 PMCID: PMC5408791 DOI: 10.1093/bioinformatics/btw838

Abstract

MOTIVATION: Flux balance analysis and its variants are widely used methods for predicting steady-state reaction rates in biochemical reaction networks. The exploration of high dimensional networks with such methods is currently hampered by software performance limitations.

RESULTS: DistributedFBA.jl is a high-level, high-performance, open-source implementation of flux balance analysis in Julia. It is tailored to solve multiple flux balance analyses on a subset or all the reactions of large and huge-scale networks, on any number of threads or nodes.

AVAILABILITY AND IMPLEMENTATION: The code is freely available on github.com/opencobra/COBRA.jl. The documentation can be found at opencobra.github.io/COBRA.jl.

CONTACT: [email protected].

SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

© The Author 2017. Published by Oxford University Press.

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