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Can J Kidney Health Dis. 2017 Apr 11;4:2054358117703071. doi: 10.1177/2054358117703071. eCollection 2017.

Kidney Disease Among Registered Métis Citizens of Ontario: A Population-Based Cohort Study.

Canadian journal of kidney health and disease

Jade S Hayward, Eric McArthur, Danielle M Nash, Jessica M Sontrop, Storm J Russell, Saba Khan, Jennifer D Walker, Gihad E Nesrallah, Manish M Sood, Amit X Garg

Affiliations

  1. Institute for Clinical Evaluative Sciences Western, London, Ontario, Canada.
  2. Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada.
  3. The Métis Nation of Ontario, Ottawa, Canada.
  4. School of Rural and Northern Health, Laurentian University, Sudbury, Ontario, Canada.
  5. Department of Nephrology, Humber River Regional Hospital, Toronto, Ontario, Canada.
  6. Division of Nephrology, Department of Medicine, The Ottawa Hospital and Kidney Research Centre, Ottawa Hospital Research Institute, University of Ottawa, Ontario, Canada.
  7. Department of Medicine, London Health Sciences Centre, London, Ontario, Canada.

PMID: 28491337 PMCID: PMC5406217 DOI: 10.1177/2054358117703071

Abstract

BACKGROUND: Indigenous peoples in Canada have higher rates of kidney disease than non-Indigenous Canadians. However, little is known about the risk of kidney disease specifically in the Métis population in Canada.

OBJECTIVE: To compare the prevalence of chronic kidney disease and incidence of acute kidney injury and end-stage kidney disease among registered Métis citizens in Ontario and a matched sample from the general Ontario population.

DESIGN: Population-based, retrospective cohort study using data from the Métis Nation of Ontario's Citizenship Registry and administrative databases.

SETTING: Ontario, Canada; 2003-2013.

PATIENTS: Ontario residents ≥18 years.

MEASUREMENTS: Prevalence of chronic kidney disease and incidence of acute kidney injury and end-stage kidney disease. Secondary outcomes among patients hospitalized with acute kidney injury included non-recovery of kidney function and mortality within 1 year of discharge.

METHODS: Database codes and laboratory values were used to determine study outcomes. Métis citizens were matched (1:4) to Ontario residents on age, sex, and area of residence. The analysis included 12 229 registered Métis citizens and 48 916 adults from the general population.

RESULTS: We found the prevalence of chronic kidney disease was slightly higher among Métis citizens compared with the general population (3.1% vs 2.6%,

LIMITATIONS: The Métis Nation of Ontario Citizenship Registry only captures about 20% of Métis people in Ontario. Administrative health care codes used to identify kidney disease are highly specific but have low sensitivity.

CONCLUSIONS: Rates of kidney disease were similar or slightly higher for Métis citizens in Ontario compared with the matched general population.

Keywords: Métis Health; Métis Nation of Ontario; acute kidney injury; chronic kidney disease; end-stage kidney disease

Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: A.X.G. was supp

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