Can J Kidney Health Dis. 2017 Apr 11;4:2054358117703071. doi: 10.1177/2054358117703071. eCollection 2017.
Kidney Disease Among Registered Métis Citizens of Ontario: A Population-Based Cohort Study.
Canadian journal of kidney health and disease
Jade S Hayward, Eric McArthur, Danielle M Nash, Jessica M Sontrop, Storm J Russell, Saba Khan, Jennifer D Walker, Gihad E Nesrallah, Manish M Sood, Amit X Garg
Affiliations
Affiliations
- Institute for Clinical Evaluative Sciences Western, London, Ontario, Canada.
- Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada.
- The Métis Nation of Ontario, Ottawa, Canada.
- School of Rural and Northern Health, Laurentian University, Sudbury, Ontario, Canada.
- Department of Nephrology, Humber River Regional Hospital, Toronto, Ontario, Canada.
- Division of Nephrology, Department of Medicine, The Ottawa Hospital and Kidney Research Centre, Ottawa Hospital Research Institute, University of Ottawa, Ontario, Canada.
- Department of Medicine, London Health Sciences Centre, London, Ontario, Canada.
PMID: 28491337
PMCID: PMC5406217 DOI: 10.1177/2054358117703071
Abstract
BACKGROUND: Indigenous peoples in Canada have higher rates of kidney disease than non-Indigenous Canadians. However, little is known about the risk of kidney disease specifically in the Métis population in Canada.
OBJECTIVE: To compare the prevalence of chronic kidney disease and incidence of acute kidney injury and end-stage kidney disease among registered Métis citizens in Ontario and a matched sample from the general Ontario population.
DESIGN: Population-based, retrospective cohort study using data from the Métis Nation of Ontario's Citizenship Registry and administrative databases.
SETTING: Ontario, Canada; 2003-2013.
PATIENTS: Ontario residents ≥18 years.
MEASUREMENTS: Prevalence of chronic kidney disease and incidence of acute kidney injury and end-stage kidney disease. Secondary outcomes among patients hospitalized with acute kidney injury included non-recovery of kidney function and mortality within 1 year of discharge.
METHODS: Database codes and laboratory values were used to determine study outcomes. Métis citizens were matched (1:4) to Ontario residents on age, sex, and area of residence. The analysis included 12 229 registered Métis citizens and 48 916 adults from the general population.
RESULTS: We found the prevalence of chronic kidney disease was slightly higher among Métis citizens compared with the general population (3.1% vs 2.6%,
LIMITATIONS: The Métis Nation of Ontario Citizenship Registry only captures about 20% of Métis people in Ontario. Administrative health care codes used to identify kidney disease are highly specific but have low sensitivity.
CONCLUSIONS: Rates of kidney disease were similar or slightly higher for Métis citizens in Ontario compared with the matched general population.
Keywords: Métis Health; Métis Nation of Ontario; acute kidney injury; chronic kidney disease; end-stage kidney disease
Conflict of interest statement
Declaration of Conflicting Interests: The author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: A.X.G. was supp
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