Display options
Share it on

Am J Geriatr Psychiatry. 1993 Summer;1(3):244-248. doi: 10.1097/00019442-199300130-00009. Epub 2013 Jan 28.

Response to Combination Cholinergic/Noradrenergic Treatments in a Patient With Alzheimer's Disease.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

Paul S Aisen, Linda M Bierer, Michael Davidson, Theresa M Ryan, Ranti Kaminsky, Kenneth L Davis

Affiliations

  1. Department of Psychiatry, Box 1230, Mt. Sinai Medical Center, 1 Gustave L. Levy PI., New York, NY 10029.

PMID: 28530925 DOI: 10.1097/00019442-199300130-00009

Abstract

A patient with probable Alzheimer's disease participated in four studies involving cholinergic and combination cholinergic/noradrenergic treatment regimens. This patient demonstrated clinically significant improvement only with the combination of physostigmine and clonidine. The implications of these findings are discussed with regard to strategies for neurotransmitter augmentation therapy for Alzheimer's disease.

Copyright © 1993 American Association for Geriatric Psychiatry. Published by Elsevier Inc. All rights reserved.

Publication Types