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Exp Ther Med. 2017 May;13(5):2405-2410. doi: 10.3892/etm.2017.4237. Epub 2017 Mar 20.

Immunosuppressive effect of sinomenine in an allergic rhinitis mouse model.

Experimental and therapeutic medicine

Zhe Chen, Ze-Zhang Tao, Xu-Hong Zhou, Ting-Ting Wu, Lin-Feng Ye

Affiliations

  1. Department of Otolaryngology Head and Neck Surgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430072, P.R. China.
  2. Department of Otolaryngology Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, P.R. China.

PMID: 28565855 PMCID: PMC5443201 DOI: 10.3892/etm.2017.4237

Abstract

Allergic rhinitis (AR) is a chronic allergic airway disease that has become a significant global public health issue. Sinomenine (SN), a natural phytochemical found in

Keywords: BALB/c mouse; allergic rhinitis; immunosuppression; sinomenine; transforming growth factor-β

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