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Cardiovasc Diagn Ther. 2017 Jun;7(3):244-251. doi: 10.21037/cdt.2017.01.16.

A comparison of Cornell and Sokolow-Lyon electrocardiographic criteria for left ventricular hypertrophy in a military male population in Taiwan: the Cardiorespiratory fitness and HospItalization Events in armed Forces study.

Cardiovascular diagnosis and therapy

Fang-Ying Su, Yi-Hwei Li, Yen-Po Lin, Chung-Jen Lee, Chih-Hung Wang, Fan-Chun Meng, Yun-Shun Yu, Felicia Lin, Hsien-Tsai Wu, Gen-Min Lin

Affiliations

  1. Department of Public Health, Tzu Chi University, Hualien, Taiwan.
  2. Department of Emergency Medicine, Tzu Chi General Hospital, Taipei branch, New Taipei City, Taiwan.
  3. Department of Nursing, Tzu Chi College of Technology, Hualien, Taiwan.
  4. Department of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
  5. Department of Electrical Engineering, National Dong Hwa University, Hualien, Taiwan.
  6. Department of Medicine, Hualien-Armed Forces General Hospital, Hualien, Taiwan.

PMID: 28567350 PMCID: PMC5440264 DOI: 10.21037/cdt.2017.01.16

Abstract

BACKGROUND: The Cornell and Sokolow-Lyon electrocardiography (ECG) criteria have been widely used for diagnosing left ventricular hypertrophy (LVH) in patients with hypertension. However, the correlations of these ECG criteria with LVH were rarely compared in military members who received rigorous training, particularly of the Asian male population.

METHODS: We compared the Cornell voltage and product criteria with the Sokolow-Lyon criteria for the echocardiographic LVH in 539 military male members, ages 18-50 years and free of hypertension in the Cardiorespiratory fitness and HospItalization Events in armed Forces (CHIEF) study in Taiwan. Pearson's correlation coefficient was used to determine the association of each ECG criterion with the index of left ventricular mass (LVM, g)/height (m)

RESULTS: The correlations of the Cornell voltage and product criteria (r=0.24 and 0.26 respectively, both P<0.0001) were stronger than that of the Sokolow-Lyon criteria (r=0.049 and 0.095, and P=0.26 and 0.03 respectively) with the LVM index. Similarly the performances of the Cornell voltage and product criteria for the echocardiographic LVH [area under curve (AUC): 0.66 and 0.68, both P<0.0001] were superior to that of the Sokolow-Lyon criteria (AUC: 0.54 and 0.53, both P>0.1) in the area under the ROC curve analysis.

CONCLUSIONS: The Cornell ECG criteria for the echocardiographic LVH had better performance than the Sokolow-Lyon criteria in a young military male cohort in Taiwan.

Keywords: Cornell criteria; Sokolow-Lyon criteria; echocardiography; electrocardiography (ECG); left ventricular hypertrophy (LVH)

Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

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