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Am J Hum Biol. 1993;5(6):725-734. doi: 10.1002/ajhb.1310050616.

Quantitative genetics of sexual dimorphism in body fat measurements.

American journal of human biology : the official journal of the Human Biology Council

Anthony G Comuzzie, John Blangero, Michael C Mahaney, Braxton D Mitchell, Michael P Stern, Jean W Maccluer

Affiliations

  1. Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas 78228.
  2. Division of Clinical Epidemiology, Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78228.

PMID: 28548357 DOI: 10.1002/ajhb.1310050616

Abstract

A variance decomposition analysis using maximum likelihood methods was employed to examine the genetic architecture of sexual dimorphism in anthropometric traits in a large pedigreed sample of Mexican American individuals from San Antonio, Texas. For this analysis the magnitude of sexual dimorphism was viewed as arising from a special case of genotype by environment interaction (G × E), that of genotype by sex (G × S). Evidence indicates a marked G × S interaction for 9 of the 12 traits examined and 1 of the 4 indices, findings which are interpreted as indicators of a strong genetic component to the degree of sexual dimorphism expressed in these traits. Such results have important implications for the use and interpretation of these traits in an epidemiological as well as an evolutionary context. © 1993 Wiley-Liss, Inc.

Copyright © 1993 Wiley-Liss, Inc., A Wiley Company.

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