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Showing 1 to 12 of 17 entries
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Quantitative genetics of sexual dimorphism in body fat measurements.

American journal of human biology : the official journal of the Human Biology Council

Comuzzie AG, Blangero J, Mahaney MC, Mitchell BD, Stern MP, Maccluer JW.
PMID: 28548357
Am J Hum Biol. 1993;5(6):725-734. doi: 10.1002/ajhb.1310050616.

A variance decomposition analysis using maximum likelihood methods was employed to examine the genetic architecture of sexual dimorphism in anthropometric traits in a large pedigreed sample of Mexican American individuals from San Antonio, Texas. For this analysis the magnitude...

Genome-wide association analysis confirms and extends the association of SLC2A9 with serum uric acid levels to Mexican Americans.

Frontiers in genetics

Voruganti VS, Kent JW, Debnath S, Cole SA, Haack K, Göring HH, Carless MA, Curran JE, Johnson MP, Almasy L, Dyer TD, Maccluer JW, Moses EK, Abboud HE, Mahaney MC, Blangero J, Comuzzie AG.
PMID: 24379826
Front Genet. 2013 Dec 16;4:279. doi: 10.3389/fgene.2013.00279. eCollection 2013.

Increased serum uric acid (SUA) is a risk factor for gout and renal and cardiovascular disease (CVD). The purpose of this study was to identify genetic factors that affect the variation in SUA in 632 Mexican Americans participants of...

Replication of Integrative Data Analysis for Adipose Tissue Dysfunction, Low-Grade Inflammation, Postprandial Responses and OMICs Signatures in Symptom-Free Adults.

Biology

Gallegos-Cabriales EC, Rodriguez-Ayala E, Laviada-Molina HA, Nava-Gonzalez EJ, Salinas-Osornio RA, Orozco L, Leal-Berumen I, Castillo-Pineda JC, Gonzalez-Lopez L, Escudero-Lourdes C, Cornejo-Barrera J, Escalante-Araiza F, Huerta-Avila EE, Buenfil-Rello FA, Peschard VG, Silva E, Veloz-Garza RA, Martinez-Hernandez A, Barajas-Olmos FM, Molina-Segui F, Gonzalez-Ramirez L, Arjona-Villicaña RD, Hernandez-Escalante VM, Gaytan-Saucedo JF, Vaquera Z, Acebo-Martinez M, Murillo-Ramirez A, Diaz-Tena SP, Figueroa-Nuñez B, Valencia-Rendon ME, Garzon-Zamora R, Viveros-Paredes JM, Valdovinos-Chavez SB, Comuzzie AG, Haack K, Thorsell AA, Han X, Cole SA, Bastarrachea RA.
PMID: 34943258
Biology (Basel). 2021 Dec 16;10(12). doi: 10.3390/biology10121342.

We previously reported preliminary characterization of adipose tissue (AT) dysfunction through the adiponectin/leptin ratio (ALR) and fasting/postprandial (F/P) gene expression in subcutaneous (SQ) adipose tissue (AT) biopsies obtained from participants in the GEMM study, a precision medicine research project....

Growth and nutritional status of the Evenki reindeer herders of Siberia.

American journal of human biology : the official journal of the Human Biology Council

Leonard WR, Katzmarzyk PT, Comuzzie AG, Crawford MH, Sukernik RI.
PMID: 28548441
Am J Hum Biol. 1994;6(3):339-350. doi: 10.1002/ajhb.1310060309.

This study examines physical growth and nutritional status in a sample of 478 (247 males; 231 females) Evenki herders of Central Siberia. The Evenki display slow growth in stature and body weight, particularly during late childhood and adolescence. Adult...

Correlates of low serum lipid levels among the Evenki herders of Siberia.

American journal of human biology : the official journal of the Human Biology Council

Leonard WR, Crawford MH, Comuzzie AG, Sukernik RI.
PMID: 28548444
Am J Hum Biol. 1994;6(3):329-338. doi: 10.1002/ajhb.1310060308.

This study examines serum lipid levels (total, HDL and LDL cholesterol, and triglycerides) among the Evenki reindeer herders of Central Siberia. Cholesterol and triglyceride levels among the Evenki are low, even relative to other indigenous arctic and herding populations....

A quantitative trait locus on chromosome 5p influences d-dimer levels in the san antonio family heart study.

International journal of vascular medicine

Diego VP, Almasy L, Rainwater DL, Mahaney MC, Comuzzie AG, Cole SA, Tracy RP, Stern MP, Maccluer JW, Blangero J.
PMID: 21151504
Int J Vasc Med. 2010;2010:490241. doi: 10.1155/2010/490241. Epub 2010 Jun 27.

Background. D-dimer is associated with increasing severity of atherosclerosis and with increased risk of a cardiovascular disease (CVD). Methods and Results. To better understand this risk factor, we performed a genome scan on 803 (301 males and 502 females)...

Replication of obesity and diabetes-related SNP associations in individuals from Yucatán, México.

Frontiers in genetics

Hernandez-Escalante VM, Nava-Gonzalez EJ, Voruganti VS, Kent JW, Haack K, Laviada-Molina HA, Molina-Segui F, Gallegos-Cabriales EC, Lopez-Alvarenga JC, Cole SA, Mezzles MJ, Comuzzie AG, Bastarrachea RA.
PMID: 25477898
Front Genet. 2014 Nov 18;5:380. doi: 10.3389/fgene.2014.00380. eCollection 2014.

The prevalence of type 2 diabetes (T2D) is rising rapidly and in Mexicans is ~19%. T2D is affected by both environmental and genetic factors. Although specific genes have been implicated in T2D risk few of these findings are confirmed...

Replication of Integrative Data Analysis for Adipose Tissue Dysfunction, Low-Grade Inflammation, Postprandial Responses and OMICs Signatures in Symptom-Free Adults.

Biology

Gallegos-Cabriales EC, Rodriguez-Ayala E, Laviada-Molina HA, Nava-Gonzalez EJ, Salinas-Osornio RA, Orozco L, Leal-Berumen I, Castillo-Pineda JC, Gonzalez-Lopez L, Escudero-Lourdes C, Cornejo-Barrera J, Escalante-Araiza F, Huerta-Avila EE, Buenfil-Rello FA, Peschard VG, Silva E, Veloz-Garza RA, Martinez-Hernandez A, Barajas-Olmos FM, Molina-Segui F, Gonzalez-Ramirez L, Arjona-Villicaña RD, Hernandez-Escalante VM, Gaytan-Saucedo JF, Vaquera Z, Acebo-Martinez M, Murillo-Ramirez A, Diaz-Tena SP, Figueroa-Nuñez B, Valencia-Rendon ME, Garzon-Zamora R, Viveros-Paredes JM, Valdovinos-Chavez SB, Comuzzie AG, Haack K, Thorsell AA, Han X, Cole SA, Bastarrachea RA.
PMID: 34943258
Biology (Basel). 2021 Dec 16;10(12). doi: 10.3390/biology10121342.

We previously reported preliminary characterization of adipose tissue (AT) dysfunction through the adiponectin/leptin ratio (ALR) and fasting/postprandial (F/P) gene expression in subcutaneous (SQ) adipose tissue (AT) biopsies obtained from participants in the GEMM study, a precision medicine research project....

Replication of Integrative Data Analysis for Adipose Tissue Dysfunction, Low-Grade Inflammation, Postprandial Responses and OMICs Signatures in Symptom-Free Adults.

Biology

Gallegos-Cabriales EC, Rodriguez-Ayala E, Laviada-Molina HA, Nava-Gonzalez EJ, Salinas-Osornio RA, Orozco L, Leal-Berumen I, Castillo-Pineda JC, Gonzalez-Lopez L, Escudero-Lourdes C, Cornejo-Barrera J, Escalante-Araiza F, Huerta-Avila EE, Buenfil-Rello FA, Peschard VG, Silva E, Veloz-Garza RA, Martinez-Hernandez A, Barajas-Olmos FM, Molina-Segui F, Gonzalez-Ramirez L, Arjona-Villicaña RD, Hernandez-Escalante VM, Gaytan-Saucedo JF, Vaquera Z, Acebo-Martinez M, Murillo-Ramirez A, Diaz-Tena SP, Figueroa-Nuñez B, Valencia-Rendon ME, Garzon-Zamora R, Viveros-Paredes JM, Valdovinos-Chavez SB, Comuzzie AG, Haack K, Thorsell AA, Han X, Cole SA, Bastarrachea RA.
PMID: 34943258
Biology (Basel). 2021 Dec 16;10(12). doi: 10.3390/biology10121342.

We previously reported preliminary characterization of adipose tissue (AT) dysfunction through the adiponectin/leptin ratio (ALR) and fasting/postprandial (F/P) gene expression in subcutaneous (SQ) adipose tissue (AT) biopsies obtained from participants in the GEMM study, a precision medicine research project....

Early endothelial damage detected by circulating particles in baboons fed a diet high in simple carbohydrates in conjunction with saturated or unsaturated fat.

American journal of cardiovascular disease

Shi Q, Hodara V, Meng Q, Voruganti VS, Rice K, Michalek JE, Comuzzie AG, VandeBerg JL.
PMID: 25360390
Am J Cardiovasc Dis. 2014 Oct 11;4(3):123-32. eCollection 2014.

Studies have shown that high-fat diets cause blood vessel damage, however, assessing pathological effects accurately and efficiently is difficult. In this study, we measured particle levels of static endothelium (CD31+ and CD105+) and activated endothelium (CD62E+, CD54+ and CD106+)...

Changes in Cerebral Blood Flow during an Alteration in Glycemic State in a Large Non-human Primate (.

Frontiers in neuroscience

Kochunov P, Wey HY, Fox PT, Lancaster JL, Davis MD, Wang DJ, Lin AL, Bastarrachea RA, Andrade MC, Mattern V, Frost P, Higgins PB, Comuzzie AG, Voruganti VS.
PMID: 28261040
Front Neurosci. 2017 Feb 14;11:49. doi: 10.3389/fnins.2017.00049. eCollection 2017.

Changes in cerebral blood flow (CBF) during a hyperglycemic challenge were mapped, using perfusion-weighted MRI, in a group of non-human primates. Seven female baboons were fasted for 16 h prior to 1-h imaging experiment, performed under general anesthesia, that...

Evaluation of estimated genetic values and their application to genome-wide investigation of systolic blood pressure.

BMC proceedings

Quillen EE, Voruganti VS, Chittoor G, Rubicz R, Peralta JM, Almeida MA, Kent JW, Diego VP, Dyer TD, Comuzzie AG, Göring HH, Duggirala R, Almasy L, Blangero J.
PMID: 25519398
BMC Proc. 2014 Jun 17;8:S66. doi: 10.1186/1753-6561-8-S1-S66. eCollection 2014.

The concept of breeding values, an individual's phenotypic deviation from the population mean as a result of the sum of the average effects of the genes they carry, is of great importance in livestock, aquaculture, and cash crop industries...

Showing 1 to 12 of 17 entries