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Lacerda EM, Bowman EW, Cliff JM, et al. The UK ME/CFS Biobank for biomedical research on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Multiple Sclerosis. Open J Bioresour. 2017;4doi: 10.5334/ojb.28.
Lacerda, E. M., Bowman, E. W., Cliff, J. M., Kingdon, C. C., King, E. C., Lee, J. S., Clark, T. G., Dockrell, H. M., Riley, E. M., Curran, H., & Nacul, L. (2017). The UK ME/CFS Biobank for biomedical research on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Multiple Sclerosis. Open journal of bioresources, 4. https://doi.org/10.5334/ojb.28
Lacerda, Eliana M, et al. "The UK ME/CFS Biobank for biomedical research on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Multiple Sclerosis." Open journal of bioresources vol. 4 (2017). doi: https://doi.org/10.5334/ojb.28
Lacerda EM, Bowman EW, Cliff JM, Kingdon CC, King EC, Lee JS, Clark TG, Dockrell HM, Riley EM, Curran H, Nacul L. The UK ME/CFS Biobank for biomedical research on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Multiple Sclerosis. Open J Bioresour. 2017;4. doi: 10.5334/ojb.28. Epub 2017 Feb 20. PMID: 28649428; PMCID: PMC5482226.
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Open J Bioresour. 2017;4. doi: 10.5334/ojb.28. Epub 2017 Feb 20.

The UK ME/CFS Biobank for biomedical research on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Multiple Sclerosis.

Open journal of bioresources

Eliana M Lacerda, Erinna W Bowman, Jacqueline M Cliff, Caroline C Kingdon, Elizabeth C King, Ji-Sook Lee, Taane G Clark, Hazel M Dockrell, Eleanor M Riley, Hayley Curran, Luis Nacul

Affiliations

  1. CureME Research Team, International Centre for Evidence in Disability (ICED), Department of Clinical Research (CRD), Faculty of Infectious and Tropical Diseases at the London School of Hygiene & Tropical Medicine, Keppel St, London WC1E 7HT, UK.
  2. Department of Immunology & Infection, Faculty of Infectious and Tropical Diseases at the London School of Hygiene & Tropical Medicine, Keppel St, London WC1E 7HT, UK.
  3. Department of Pathogen Molecular Biology, Faculty of Infectious and Tropical Diseases at the London School of Hygiene & Tropical Medicine, Keppel St, London WC1E 7HT, UK.

PMID: 28649428 PMCID: PMC5482226 DOI: 10.5334/ojb.28

Abstract

The UK ME/CFS Biobank was launched in August 2011 following extensive consultation with professionals and patient representatives. The bioresource aims to enhance research on myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), related to pathophysiology, biomarkers and therapeutic approaches. The cohort includes 18-60 year olds, encompassing 284 clinically-confirmed ME/CFS cases, 60 neurologist-diagnosed multiple sclerosis (MS) cases, and 135 healthy individuals. The Biobank contains blood samples, aliquoted into serum, plasma, peripheral blood mononuclear cells (PBMC), red blood cells/granulocyte pellet, whole blood, and RNA (totalling 29,863 aliquots). Extensive dataset (700 clinical and socio-demographic variables/participant) enables comprehensive phenotyping. Potential reuse is conditional to ethical approval.

Keywords: Myalgic Encephalomyelitis / Chronic Fatigue Syndrome; biobank; biospecimen; database; multiple sclerosis

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