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McGranahan N, Swanton C. Cancer Evolution Constrained by the Immune Microenvironment. Cell. 2017;170(5):825-827doi: 10.1016/j.cell.2017.08.012.
McGranahan, N., & Swanton, C. (2017). Cancer Evolution Constrained by the Immune Microenvironment. Cell, 170(5), 825-827. https://doi.org/10.1016/j.cell.2017.08.012
McGranahan, Nicholas, and Swanton, Charles. "Cancer Evolution Constrained by the Immune Microenvironment." Cell vol. 170,5 (2017): 825-827. doi: https://doi.org/10.1016/j.cell.2017.08.012
McGranahan N, Swanton C. Cancer Evolution Constrained by the Immune Microenvironment. Cell. 2017 Aug 24;170(5):825-827. doi: 10.1016/j.cell.2017.08.012. PMID: 28841415.
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Cell. 2017 Aug 24;170(5):825-827. doi: 10.1016/j.cell.2017.08.012.

Cancer Evolution Constrained by the Immune Microenvironment.

Cell

Nicholas McGranahan, Charles Swanton

Affiliations

  1. Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London, WC1E 6BT, UK.
  2. Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London, WC1E 6BT, UK; Translational Cancer Therapeutics Laboratory, The Francis Crick Institute, 1 Midland Rd, London, NW1 1AT, UK. Electronic address: [email protected].

PMID: 28841415 DOI: 10.1016/j.cell.2017.08.012

Abstract

Tumor development is a Darwinian evolutionary process, involving the interplay between cancer subclones and the local immune microenvironment. These complex interactions are highlighted in this issue of Cell by the results from Jiménez-Sánchez et al. of a deep analysis of one patient with advanced serous carcinoma of the ovary.

Copyright © 2017. Published by Elsevier Inc.

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