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Oncotarget. 2017 Jul 17;8(38):64050-64065. doi: 10.18632/oncotarget.19300. eCollection 2017 Sep 08.

Sp110 enhances macrophage resistance to .

Oncotarget

Yongyan Wu, Zekun Guo, Fayang Liu, Kezhen Yao, Mingqing Gao, Yan Luo, Yong Zhang

Affiliations

  1. Shanxi Key Laboratory of Otorhinolaryngology Head and Neck Cancer, Department of Otolaryngology, Head & Neck Surgery, The First Hospital, Shanxi Medical University, Taiyuan 030001, Shanxi, China.
  2. College of Veterinary Medicine, Northwest A&F University, Yangling 712100, Shaanxi, China.
  3. Key Laboratory of Animal Biotechnology, Ministry of Agriculture, Northwest A&F University, Yangling 712100, Shaanxi, China.

PMID: 28969051 PMCID: PMC5609983 DOI: 10.18632/oncotarget.19300

Abstract

Tuberculosis remains a leading health problem worldwide and still accounts for about 1.3 million deaths annually. Expression of the mouse Sp110 nuclear body protein (Sp110) upregulates the apoptotic pathway, which plays an essential role in enhancing host immunity to

Keywords: Mycobacterium tuberculosis; Sp110; apoptosis; endoplasmic reticulum stress; protein interactome

Conflict of interest statement

CONFLICTS OF INTEREST The authors declare that they have no conflicts of interest with the contents of this article.

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