Display options
Cite
Bruserud Ø, Bratland E, Hellesen A, et al. Altered Immune Activation and IL-23 Signaling in Response to . Front Immunol. 2017;8:1074doi: 10.3389/fimmu.2017.01074.
Bruserud, �. �., Bratland, E., Hellesen, A., Delaleu, N., Reikvam, H., Oftedal, B. E., & Wolff, A. S. B. (2017). Altered Immune Activation and IL-23 Signaling in Response to . Frontiers in immunology, 81074. https://doi.org/10.3389/fimmu.2017.01074
Bruserud, Øyvind, et al. "Altered Immune Activation and IL-23 Signaling in Response to ." Frontiers in immunology vol. 8 (2017): 1074. doi: https://doi.org/10.3389/fimmu.2017.01074
Bruserud Ø, Bratland E, Hellesen A, Delaleu N, Reikvam H, Oftedal BE, Wolff ASB. Altered Immune Activation and IL-23 Signaling in Response to . Front Immunol. 2017 Sep 01;8:1074. doi: 10.3389/fimmu.2017.01074. eCollection 2017. PMID: 28919897; PMCID: PMC5585148.
Copy Download .nbib Format: NLM
Share it on

Front Immunol. 2017 Sep 01;8:1074. doi: 10.3389/fimmu.2017.01074. eCollection 2017.

Altered Immune Activation and IL-23 Signaling in Response to .

Frontiers in immunology

Øyvind Bruserud, Eirik Bratland, Alexander Hellesen, Nicolas Delaleu, Håkon Reikvam, Bergithe E Oftedal, Anette S B Wolff

Affiliations

  1. Department of Clinical Science, University of Bergen, Bergen, Norway.
  2. Broegelmann Research Laboratory, Department of Clinical Science, University of Bergen, Bergen, Norway.
  3. Swiss Institute of Bioinformatics, Lausanne, Switzerland.
  4. Computational Biology Unit, Department of Informatics, University of Bergen, Bergen, Norway.
  5. Department of Medicine, Haukeland University Hospital, Bergen, Norway.

PMID: 28919897 PMCID: PMC5585148 DOI: 10.3389/fimmu.2017.01074

Abstract

OBJECTIVE: Autoimmune polyendocrine syndrome type 1 (APS-1) is a rare, childhood onset disease caused by mutations in the

METHODS: Whole blood was stimulated with

RESULTS: We found an altered immune response in APS-1 patients compared with healthy controls. Patients fail to increase the essential ILs, such as IL-2, IL-17A, IL-22, and IL-23, when stimulating whole blood with

CONCLUSION: APS-1 patients have an altered immune response to

Keywords: IL-17; IL-22; IL-23; autoimmune polyendocrine syndrome type 1; chronic mucocutaneous candidiasis; monocytes

References

  1. J Clin Endocrinol Metab. 2004 Feb;89(2):557-62 - PubMed
  2. Curr Opin Rheumatol. 2014 Jul;26(4):361-70 - PubMed
  3. Nat Genet. 1997 Dec;17(4):393-8 - PubMed
  4. JCI Insight. 2016 Aug 18;1(13):null - PubMed
  5. J Clin Endocrinol Metab. 2006 Aug;91(8):2843-50 - PubMed
  6. Bioinformatics. 2011 Feb 1;27(3):431-2 - PubMed
  7. J Immunol. 2011 Aug 15;187(4):2023-30 - PubMed
  8. Nat Rev Immunol. 2011 Apr;11(4):275-88 - PubMed
  9. J Clin Endocrinol Metab. 2012 Apr;97(4):1114-24 - PubMed
  10. F1000Res. 2015 Dec 17;4:null - PubMed
  11. J Biol Chem. 2001 Jun 1;276(22):19597-602 - PubMed
  12. J Immunol. 2008 Mar 15;180(6):3824-32 - PubMed
  13. Nat Commun. 2013;4:1342 - PubMed
  14. Blood. 1994 Dec 15;84(12):4008-27 - PubMed
  15. Nat Genet. 1997 Dec;17(4):399-403 - PubMed
  16. J Immunol. 2010 Nov 1;185(9):5453-62 - PubMed
  17. Curr Protoc Bioinformatics. 2008 Mar;Chapter 7:Unit 7.3 - PubMed
  18. J Exp Med. 2010 Feb 15;207(2):291-7 - PubMed
  19. Immunology. 2011 Sep;134(1):60-72 - PubMed
  20. Curr Opin Immunol. 2016 Dec;43:8-15 - PubMed
  21. Medicine (Baltimore). 2013 Mar;92 (2):109-22 - PubMed
  22. Scand J Immunol. 2010 Jun;71(6):459-67 - PubMed
  23. J Clin Endocrinol Metab. 2007 Feb;92(2):595-603 - PubMed
  24. Ann N Y Acad Sci. 2011 Dec;1246:77-91 - PubMed
  25. Clin Exp Immunol. 2008 Dec;154(3):406-14 - PubMed
  26. Curr Opin Microbiol. 2008 Aug;11(4):313-7 - PubMed
  27. Clin Endocrinol (Oxf). 2001 Feb;54(2):211-7 - PubMed
  28. J Intern Med. 2009 May;265(5):514-29 - PubMed
  29. World J Gastroenterol. 2015 May 21;21(19):5823-30 - PubMed
  30. Nat Rev Immunol. 2008 Dec;8(12):948-57 - PubMed
  31. Clin Exp Immunol. 2009 Apr;156(1):40-51 - PubMed
  32. Curr Opin Allergy Clin Immunol. 2015 Feb;15(1):104-9 - PubMed
  33. Immun Inflamm Dis. 2016 May 25;4(2):235-243 - PubMed
  34. Horm Res Paediatr. 2010;73(6):449-57 - PubMed
  35. J Allergy Clin Immunol. 2012 Feb;129(2):464-72, 472.e1-3 - PubMed
  36. Nat Rev Immunol. 2015 Oct;15(10):630-42 - PubMed
  37. Bioinformatics. 2013 Mar 1;29(5):661-3 - PubMed
  38. J Clin Endocrinol Metab. 2016 Aug;101(8):2975-83 - PubMed
  39. Medicine (Baltimore). 2010 Nov;89(6):381-402 - PubMed
  40. Science. 2002 Nov 15;298(5597):1395-401 - PubMed
  41. Immunity. 2000 Nov;13(5):715-25 - PubMed
  42. Autoimmun Rev. 2014 Apr-May;13(4-5):496-502 - PubMed
  43. J Clin Immunol. 2013 Nov;33(8):1341-8 - PubMed
  44. J Allergy Clin Immunol. 2010 Nov;126(5):1006-15, 1015.e1-4 - PubMed
  45. Science. 2015 May 1;348(6234):589-94 - PubMed
  46. Blood. 2008 Oct 1;112(7):2657-66 - PubMed
  47. J Exp Med. 2010 Feb 15;207(2):299-308 - PubMed
  48. Hum Genet. 1998 Oct;103(4):428-34 - PubMed
  49. Eur J Immunol. 2011 Jan;41(1):235-45 - PubMed

Publication Types