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Oncotarget. 2017 Aug 24;8(43):74917-74926. doi: 10.18632/oncotarget.20459. eCollection 2017 Sep 26.

A genome-wide association analysis identifies .

Oncotarget

Mai Kimura, Yuichi Tamura, Christophe Guignabert, Makoto Takei, Kenjiro Kosaki, Nobuhiro Tanabe, Koichiro Tatsumi, Tsutomu Saji, Toru Satoh, Masaharu Kataoka, Shigeo Kamitsuji, Naoyuki Kamatani, Raphaël Thuillet, Ly Tu, Marc Humbert, Keiichi Fukuda, Motoaki Sano

Affiliations

  1. Department of Cardiology, Keio University School of Medicine, Tokyo, Japan.
  2. Univ Paris-Sud, Université Paris-Saclay, Le Kremlin-Bicêtre, France.
  3. AP-HP, Service de Pneumologie, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
  4. Inserm UMR_S 999, Hôpital Marie Lannelongue, Le Plessis-Robinson, France.
  5. Department of Cardiology, International University of Health and Welfare Mita Hospital, Tokyo, Japan.
  6. Center for Medical Genetics, Keio University School of Medicine, Tokyo, Japan.
  7. Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan.
  8. Department of Advanced Medicine in Pulmonary Hypertension, Graduate School of Medicine, Chiba University, Chiba, Japan.
  9. Department of Pediatrics, Toho University, Medical Center, Omori Hospital, Tokyo, Japan.
  10. Department of Cardiology, Kyorin University School of Medicine, Tokyo, Japan.
  11. StaGen Co. Ltd., Tokyo, Japan.

PMID: 29088834 PMCID: PMC5650389 DOI: 10.18632/oncotarget.20459

Abstract

Pulmonary arterial hypertension (PAH) is a lethal disease that often affects the young. Although

Keywords: genome-wide association study; novel therapeutic target; pulmonary arterial hypertension

Conflict of interest statement

CONFLICTS OF INTEREST The authors declare no competing financial interests.

References

  1. Biometrics. 1999 Dec;55(4):997-1004 - PubMed
  2. Nat Genet. 2006 Aug;38(8):904-9 - PubMed
  3. Nat Rev Drug Discov. 2014 Apr;13(4):290-314 - PubMed
  4. PLoS One. 2012;7(9):e45834 - PubMed
  5. N Engl J Med. 2009 Nov 5;361(19):1864-71 - PubMed
  6. Pharmacogenomics J. 2013 Feb;13(1):60-9 - PubMed
  7. Am J Respir Crit Care Med. 2012 Nov 1;186(9):892-6 - PubMed
  8. Nat Genet. 2000 Sep;26(1):81-4 - PubMed
  9. Cell Signal. 2002 Jan;14(1):53-60 - PubMed
  10. Nat Genet. 2013 May;45(5):518-21 - PubMed
  11. Schizophr Res. 2008 Apr;101(1-3):36-49 - PubMed
  12. Handb Exp Pharmacol. 2011;(204):237-49 - PubMed
  13. Biochim Biophys Acta. 2001 Jan 26;1517(2):278-87 - PubMed
  14. Hum Mol Genet. 2014 Dec 15;23(24):6668-76 - PubMed
  15. Nat Genet. 2013 Jun;45(6):676-9 - PubMed
  16. Nat Genet. 2003 Oct;35(2):131-8 - PubMed
  17. J Cardiovasc Med (Hagerstown). 2011 Feb;12(2):88-95 - PubMed
  18. Lancet. 2006 Nov 18;368(9549):1795-809 - PubMed
  19. Am J Physiol Lung Cell Mol Physiol. 2006 Apr;290(4):L723-L729 - PubMed
  20. Chest. 2015 Feb;147(2):529-537 - PubMed
  21. Am J Physiol Lung Cell Mol Physiol. 2007 Jan;292(1):L294-303 - PubMed
  22. Bioinformatics. 2010 Sep 15;26(18):2336-7 - PubMed
  23. Am J Hum Genet. 2000 Sep;67(3):737-44 - PubMed
  24. Am J Hum Genet. 2007 Sep;81(3):559-75 - PubMed
  25. Ann Intern Med. 1991 Sep 1;115(5):343-9 - PubMed

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