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Horne D, Jones P, Salgaonkar V, et al. Low intensity pulsed ultrasound (LIPUS) for the treatment of intervertebral disc degeneration. Proc SPIE Int Soc Opt Eng. 2017;10066doi: 10.1117/12.2255761.
Horne, D., Jones, P., Salgaonkar, V., Adams, M., Ozilgen, B. A., Zahos, P., Tang, X., Liebenburg, E., Coughlin, D., Lotz, J., & Diederich, C. (2017). Low intensity pulsed ultrasound (LIPUS) for the treatment of intervertebral disc degeneration. Proceedings of SPIE--the International Society for Optical Engineering, 10066. https://doi.org/10.1117/12.2255761
Horne, Devante, et al. "Low intensity pulsed ultrasound (LIPUS) for the treatment of intervertebral disc degeneration." Proceedings of SPIE--the International Society for Optical Engineering vol. 10066 (2017). doi: https://doi.org/10.1117/12.2255761
Horne D, Jones P, Salgaonkar V, Adams M, Ozilgen BA, Zahos P, Tang X, Liebenburg E, Coughlin D, Lotz J, Diederich C. Low intensity pulsed ultrasound (LIPUS) for the treatment of intervertebral disc degeneration. Proc SPIE Int Soc Opt Eng. 2017 Jan-Feb;10066. doi: 10.1117/12.2255761. Epub 2017 Feb 22. PMID: 29104343; PMCID: PMC5667559.
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Proc SPIE Int Soc Opt Eng. 2017 Jan-Feb;10066. doi: 10.1117/12.2255761. Epub 2017 Feb 22.

Low intensity pulsed ultrasound (LIPUS) for the treatment of intervertebral disc degeneration.

Proceedings of SPIE--the International Society for Optical Engineering

Devante Horne, Peter Jones, Vasant Salgaonkar, Matt Adams, B Arda Ozilgen, Peter Zahos, Xinyan Tang, Ellen Liebenburg, Dezba Coughlin, Jeffrey Lotz, Chris Diederich

Affiliations

  1. UC Berkeley - UC San Francisco Graduate Program in Bioengineering, CA, USA.
  2. Department of Radiation Oncology, UC San Francisco, CA USA.
  3. Department of Orthopaedic Surgery, UC San Francisco, CA, USA.

PMID: 29104343 PMCID: PMC5667559 DOI: 10.1117/12.2255761

Abstract

Discogenic back pain presents a major public health issue, with current therapeutic interventions limited to short-term symptom relief without providing regenerative remedies for diseased intervertebral discs (IVD). Many of these interventions are invasive and can diminish the biomechanical integrity of the IVDs. Low intensity pulsed ultrasound (LIPUS) is a potential treatment option that is both non-invasive and regenerative. LIPUS has been shown to be a clinically effective method for the enhancement of wound and fracture healing. Recent

Keywords: Aggrecan; Collagen; Interleukin; Low intensity pulsed ultrasound; TNF; disc degeneration; intervertebral disc; rat tail

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