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Front Oncol. 2017 Nov 02;7:252. doi: 10.3389/fonc.2017.00252. eCollection 2017.

Development of Novel Patient-Derived Xenografts from Breast Cancer Brain Metastases.

Frontiers in oncology

María J Contreras-Zárate, D Ryan Ormond, Austin E Gillen, Colton Hanna, Nicole L Day, Natalie J Serkova, Britta M Jacobsen, Susan M Edgerton, Ann D Thor, Virginia F Borges, Kevin O Lillehei, Michael W Graner, Peter Kabos, Diana M Cittelly

Affiliations

  1. Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
  2. Department of Neurosurgery, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
  3. RNA Bioscience Initiative, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
  4. Department of Anesthesiology, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
  5. Department of Medicine, Division of Medical Oncology, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.

PMID: 29164052 PMCID: PMC5673842 DOI: 10.3389/fonc.2017.00252

Abstract

Brain metastases are an increasing burden among breast cancer patients, particularly for those with HER2

Keywords: HER2+; brain colonization; brain metastases models; breast cancer; patient-derived xenograft; triple negative

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