Front Immunol. 2017 Nov 22;8:1614. doi: 10.3389/fimmu.2017.01614. eCollection 2017.
Frontiers in immunology
Florian Sparber, Salomé LeibundGut-Landmann
PMID: 29213272 PMCID: PMC5702624 DOI: 10.3389/fimmu.2017.01614
The skin of mammalian organisms is home for a myriad of microbes. Many of these commensals are thought to have beneficial effects on the host by critically contributing to immune homeostasis. Consequently, dysbiosis can have detrimental effects for the host that may manifest with inflammatory diseases at the barrier tissue. Besides bacteria, fungi make an important contribution to the microbiota and among these, the yeast
Keywords: Malassezia; adaptive immunity; allergic response; commensalism; indoles; innate immunity; opportunistic pathogenic fungi; skin disorders