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Annu Rev Clin Psychol. 2018 May 07;14:237-258. doi: 10.1146/annurev-clinpsy-050817-084934. Epub 2018 Jan 12.

Transforming the Treatment of Schizophrenia in the United States: The RAISE Initiative.

Annual review of clinical psychology

Lisa B Dixon, Howard H Goldman, Vinod H Srihari, John M Kane, Macniven, Engelen

Affiliations

  1. New York State Psychiatric Institute, Columbia University Medical Center, New York, NY 10032, USA; email: [email protected].
  2. Department of Psychiatry, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.
  3. Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06511, USA.
  4. Zucker Hillside Hospital and the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York 11549, USA.

PMID: 29328779 DOI: 10.1146/annurev-clinpsy-050817-084934

Abstract

The schizophrenia spectrum disorders are neurodevelopmental illnesses with a lifetime prevalence near 1%, producing extensive functional impairment and low expectations for recovery. Until recently, treatment in the United States has largely attempted to stabilize individuals with chronic schizophrenia. The identification and promotion of evidence-based practices for schizophrenia via the Patient Outcomes Research Team, combined with international studies supporting the value of early intervention, provided the foundation for the Recovery After an Initial Schizophrenia Episode (RAISE) project. The RAISE studies further supported the value of reducing the duration of untreated psychosis and providing a multi-element treatment called coordinated specialty care (CSC) to improve outcomes for patients in usual treatment settings. Although CSC programs have proliferated rapidly in the United States, many challenges remain in the treatment and recovery of individuals with schizophrenia in the aftermath of RAISE.

Keywords: coordinated specialty care; first episode; psychosis; recovery; schizophrenia; treatment

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