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Clin Pract. 2018 Jun 07;8(2):1061. doi: 10.4081/cp.2018.1061. eCollection 2018 Mar 28.

Bone marrow abnormalities detected by magnetic resonance imaging as initial sign of hematologic malignancies.

Clinics and practice

Ida Sofie Grønningsæter, Aymen Bushra Ahmed, Nils Vetti, Silje Johansen, Øystein Bruserud, Håkon Reikvam

Affiliations

  1. Institute of Clinical Science, University of Bergen.
  2. Department of Medicine, Haukeland University Hospital.
  3. Radiological Department, Haukeland University Hospital, Norway.

PMID: 30069300 PMCID: PMC6047479 DOI: 10.4081/cp.2018.1061

Abstract

The increasing use of radiological examination, especially magnetic resonance imaging (MRI), will probably increase the risk of unintended discovery of bone marrow abnormalities in patients where a hematologic disease would not be expected. In this paper we present four patients with different hematologic malignancies of nonplasma cell types. In all patients the MRI bone marrow abnormalities represent an initial presentation of the disease. These case reports illustrate the importance of a careful diagnostic follow-up without delay of patients with MRI bone marrow abnormalities, because such abnormalities can represent the first sign of both acute promyelocytic leukemia as well as other variants of acute leukemia.

Keywords: Leukemia; bone marrow disease; magnetic resonance imaging

Conflict of interest statement

Conflict of interests: the authors report no potential conflict of interest.

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