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Angew Chem Int Ed Engl. 2019 Jan 28;58(5):1499-1503. doi: 10.1002/anie.201812927. Epub 2018 Dec 28.

Regioselective Vinylation of Remote Unactivated C(sp.

Angewandte Chemie (International ed. in English)

Shuo Wu, Xinxin Wu, Dongping Wang, Chen Zhu

Affiliations

  1. Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering, and Materials Science, Soochow University, 199 Ren-Ai Road, Suzhou, Jiangsu, 215123, China.

PMID: 30512239 DOI: 10.1002/anie.201812927

Abstract

Regioselective incorporation of a particular functional group into aliphatic sites by direct activation of unreactive C-H bonds is of great synthetic value. Despite advances in radical-mediated functionalization of C(sp

© 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Keywords: C−H activation; alcohols; fluorine; photocatalysis; radicals

Publication Types

Grant support