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Zhang J, He J, Johnson JL, et al. Chaperone-Mediated Autophagy Upregulation Rescues Megalin Expression and Localization in Cystinotic Proximal Tubule Cells. Front Endocrinol (Lausanne). 2019;10:21doi: 10.3389/fendo.2019.00021.
Zhang, J., He, J., Johnson, J. L., Rahman, F., Gavathiotis, E., Cuervo, A. M., & Catz, S. D. (2019). Chaperone-Mediated Autophagy Upregulation Rescues Megalin Expression and Localization in Cystinotic Proximal Tubule Cells. Frontiers in endocrinology, 1021. https://doi.org/10.3389/fendo.2019.00021
Zhang, Jinzhong, et al. "Chaperone-Mediated Autophagy Upregulation Rescues Megalin Expression and Localization in Cystinotic Proximal Tubule Cells." Frontiers in endocrinology vol. 10 (2019): 21. doi: https://doi.org/10.3389/fendo.2019.00021
Zhang J, He J, Johnson JL, Rahman F, Gavathiotis E, Cuervo AM, Catz SD. Chaperone-Mediated Autophagy Upregulation Rescues Megalin Expression and Localization in Cystinotic Proximal Tubule Cells. Front Endocrinol (Lausanne). 2019 Feb 01;10:21. doi: 10.3389/fendo.2019.00021. eCollection 2019. PMID: 30774622; PMCID: PMC6367655.
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Front Endocrinol (Lausanne). 2019 Feb 01;10:21. doi: 10.3389/fendo.2019.00021. eCollection 2019.

Chaperone-Mediated Autophagy Upregulation Rescues Megalin Expression and Localization in Cystinotic Proximal Tubule Cells.

Frontiers in endocrinology

Jinzhong Zhang, Jing He, Jennifer L Johnson, Farhana Rahman, Evripidis Gavathiotis, Ana Maria Cuervo, Sergio D Catz

Affiliations

  1. Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, United States.
  2. Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY, United States.
  3. Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY, United States.

PMID: 30774622 PMCID: PMC6367655 DOI: 10.3389/fendo.2019.00021

Abstract

Cystinosis is a lysosomal storage disorder caused by defects in

Keywords: LAMP2A; Rab 11 GTPase; chaperone-mediated autophagy (CMA); cystinosis; fanconi syndrome; lysosomal storage disorder (LSD); megalin; vesicular trafficking

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