Display options
Cite
Zhang S, Bai W, Tong X, et al. Correlation between tumor microenvironment-associated factors and the efficacy and prognosis of neoadjuvant therapy for rectal cancer. Oncol Lett. 2018;17(1):1062-1070doi: 10.3892/ol.2018.9682.
Zhang, S., Bai, W., Tong, X., Bu, P., Xu, J., & Xi, Y. (2019). Correlation between tumor microenvironment-associated factors and the efficacy and prognosis of neoadjuvant therapy for rectal cancer. Oncology letters, 17(1), 1062-1070. https://doi.org/10.3892/ol.2018.9682
Zhang, Siyu, et al. "Correlation between tumor microenvironment-associated factors and the efficacy and prognosis of neoadjuvant therapy for rectal cancer." Oncology letters vol. 17,1 (2019): 1062-1070. doi: https://doi.org/10.3892/ol.2018.9682
Zhang S, Bai W, Tong X, Bu P, Xu J, Xi Y. Correlation between tumor microenvironment-associated factors and the efficacy and prognosis of neoadjuvant therapy for rectal cancer. Oncol Lett. 2019 Jan;17(1):1062-1070. doi: 10.3892/ol.2018.9682. Epub 2018 Nov 09. PMID: 30655866; PMCID: PMC6313063.
Copy Download .nbib Format: NLM
Share it on

Oncol Lett. 2019 Jan;17(1):1062-1070. doi: 10.3892/ol.2018.9682. Epub 2018 Nov 09.

Correlation between tumor microenvironment-associated factors and the efficacy and prognosis of neoadjuvant therapy for rectal cancer.

Oncology letters

Siyu Zhang, Wenqi Bai, Xunan Tong, Peng Bu, Jing Xu, Yanfeng Xi

Affiliations

  1. Department of Pathology, Shanxi Medical University, Taiyuan, Shanxi 030001, P.R. China.
  2. Department of Colorectal Surgery, Shanxi Provincial Cancer Hospital, Taiyuan, Shanxi 030013, P.R. China.
  3. Departent of Surgery, Shanxi Medical University, Taiyuan, Shanxi 030001, P.R. China.
  4. Department of Pathology, Shanxi Provincial Cancer Hospital, Taiyuan, Shanxi 030013, P.R. China.

PMID: 30655866 PMCID: PMC6313063 DOI: 10.3892/ol.2018.9682

Abstract

The tumor microenvironment contributes to the survival and development of tumor cells and is therefore a key target for cancer therapy. The tumor microenvironment has unique physical and chemical properties and is associated with inflammation and immunity. To examine the correlation between tumor microenvironment-associated factors and the efficacy and prognosis of neoadjuvant therapy for rectal cancer, and to compare the differences between two treatments [neoadjuvant chemotherapy (NAC) vs. neoadjuvant chemoradiotherapy (NACR)], an immunohistochemical method was used to measure the expression levels of CD4

Keywords: neoadjuvant therapy; rectal cancer; tissue microarrays; tumor microenvironment; tumor-infiltrating lymphocytes

References

  1. J Immunol. 1999 May 15;162(10):5813-20 - PubMed
  2. Blood. 2001 Mar 15;97(6):1809-16 - PubMed
  3. Nat Med. 2002 Aug;8(8):793-800 - PubMed
  4. Science. 2003 Feb 14;299(5609):1057-61 - PubMed
  5. Nat Med. 2003 May;9(5):562-7 - PubMed
  6. Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10398-403 - PubMed
  7. Eur J Immunol. 2004 Dec;34(12):3485-96 - PubMed
  8. Immunity. 2004 Oct;21(4):589-601 - PubMed
  9. Nat Immunol. 2005 Apr;6(4):338-44 - PubMed
  10. Nat Med. 2007 Jan;13(1):84-8 - PubMed
  11. Immunity. 2007 Jul;27(1):111-22 - PubMed
  12. Br J Cancer. 2008 Jan 15;98(1):148-53 - PubMed
  13. Annu Rev Immunol. 2008;26:677-704 - PubMed
  14. Nat Rev Immunol. 2008 Jun;8(6):467-77 - PubMed
  15. Cancer Immunol Immunother. 2009 Aug;58(8):1219-28 - PubMed
  16. Blood. 2009 Aug 20;114(8):1545-52 - PubMed
  17. Int J Cancer. 2010 Jun 1;126(11):2635-43 - PubMed
  18. Q J Nucl Med Mol Imaging. 2010 Jun;54(3):244-8 - PubMed
  19. Cell Mol Immunol. 2010 Nov;7(6):419-27 - PubMed
  20. Int J Radiat Oncol Biol Phys. 2011 Jul 1;80(3):869-76 - PubMed
  21. Proc Natl Acad Sci U S A. 2011 May 24;108(21):8749-54 - PubMed
  22. Radiat Oncol. 2011 May 16;6:49 - PubMed
  23. Int J Cancer. 2011 Aug 15;129(4):832-8 - PubMed
  24. Immunol Res. 2011 Aug;50(2-3):269-75 - PubMed
  25. Anticancer Res. 2011 Dec;31(12):4569-74 - PubMed
  26. Cancer Immunol Immunother. 2012 Sep;61(9):1463-72 - PubMed
  27. N Engl J Med. 2012 Mar 8;366(10):925-31 - PubMed
  28. Int J Cancer. 2013 Mar 15;132(6):1341-50 - PubMed
  29. Clin Cancer Res. 2013 Jun 15;19(12):3165-75 - PubMed
  30. J Autoimmun. 2013 Sep;45:49-57 - PubMed
  31. J Clin Invest. 2013 Jul;123(7):2756-63 - PubMed
  32. Cancer Immunol Immunother. 2014 Feb;63(2):81-99 - PubMed
  33. Cancer Immunol Res. 2014 Jul;2(7):690-698 - PubMed
  34. Cancer Discov. 2015 Jan;5(1):43-51 - PubMed
  35. Breast Cancer Res. 2014 Nov 29;16(6):488 - PubMed
  36. CA Cancer J Clin. 2015 Mar;65(2):87-108 - PubMed
  37. Oncotarget. 2015 Mar 10;6(7):5449-64 - PubMed
  38. Immunol Lett. 2015 May;165(1):52-9 - PubMed
  39. Cancer Metastasis Rev. 1989 Aug;8(2):98-101 - PubMed
  40. Int J Clin Oncol. 2016 Oct;21(5):946-952 - PubMed
  41. Cancer Sci. 2018 Apr;109(4):966-979 - PubMed
  42. Int J Colorectal Dis. 1997;12(1):19-23 - PubMed

Publication Types