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Hong SP, Song S, Lee S, et al. Regenerative potential of mouse embryonic stem cell-derived PDGFRα. World J Stem Cells. 2019;11(1):44-54doi: 10.4252/wjsc.v11.i1.44.
Hong, S. P., Song, S., Lee, S., Jo, H., Kim, H. K., Han, J., Park, J. H., & Cho, S. W. (2019). Regenerative potential of mouse embryonic stem cell-derived PDGFRα. World journal of stem cells, 11(1), 44-54. https://doi.org/10.4252/wjsc.v11.i1.44
Hong, Seon Pyo, et al. "Regenerative potential of mouse embryonic stem cell-derived PDGFRα." World journal of stem cells vol. 11,1 (2019): 44-54. doi: https://doi.org/10.4252/wjsc.v11.i1.44
Hong SP, Song S, Lee S, Jo H, Kim HK, Han J, Park JH, Cho SW. Regenerative potential of mouse embryonic stem cell-derived PDGFRα. World J Stem Cells. 2019 Jan 26;11(1):44-54. doi: 10.4252/wjsc.v11.i1.44. PMID: 30705714; PMCID: PMC6354102.
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World J Stem Cells. 2019 Jan 26;11(1):44-54. doi: 10.4252/wjsc.v11.i1.44.

Regenerative potential of mouse embryonic stem cell-derived PDGFRα.

World journal of stem cells

Seon Pyo Hong, Sukhyun Song, Seungjoo Lee, Hyeonju Jo, Hyoung Kyu Kim, Jin Han, Jae-Hyeong Park, Sung Woo Cho

Affiliations

  1. Center for Vascular Research, Institute of Basic Science (IBS), Daejeon 34141, South Korea.
  2. Department of Neurosurgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, South Korea.
  3. Cardiovascular and Metabolic Disease Center, Department of Physiology, Department of Health Sciences and Technology, BK21 plus Project Team, Inje University College of Medicine, Busan 47392, South Korea.
  4. Department of Cardiology in Internal Medicine, School of Medicine, Chungnam National University Hospital, Chungnam National University, Daejeon 35015, South Korea.
  5. Division of Cardiology, Department of Internal Medicine, Inje University College of Medicine, Seoul Paik Hospital, Seoul 04551, South Korea.

PMID: 30705714 PMCID: PMC6354102 DOI: 10.4252/wjsc.v11.i1.44

Abstract

BACKGROUND: Pluripotent stem cell-derived cardiomyocytes (CMs) have become one of the most attractive cellular resources for cell-based therapy to rescue damaged cardiac tissue.

AIM: We investigated the regenerative potential of mouse embryonic stem cell (ESC)-derived platelet-derived growth factor receptor-α (DGFRα)

METHODS: We induced mouse ESCs into PDGFRα

RESULTS: Compared with the untreated MI hearts, the anterior and septal regional wall motion and systolic functional parameters were notably and similarly improved in the MI hearts implanted with PDGFRα

CONCLUSION: PDGFRα

Keywords: Cardiomyocyte; Embryonic stem cell; Myocardial infarction; Pluripotent stem cell; Regeneration

Conflict of interest statement

Conflict-of-interest statement: No potential conflicts of interest relevant to this article were reported.

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