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Ther Clin Risk Manag. 2019 Feb 07;15:251-258. doi: 10.2147/TCRM.S180170. eCollection 2019.

Impact of ST-segment elevation on the outcome of Takotsubo syndrome.

Therapeutics and clinical risk management

Thorsten Gietzen, Ibrahim El-Battrawy, Siegfried Lang, Xiao-Bo Zhou, Michael Behnes, Uzair Ansari, Martin Borggrefe, Ibrahim Akin

Affiliations

  1. First Department of Medicine, Faculty of Medicine, University Medical Centre Mannheim (UMM), University of Heidelberg, Mannheim, Germany, [email protected].
  2. German Center for Cardiovascular Research (DZHK), Partner Site, Heidelberg-Mannheim, Mannheim, Germany, [email protected].

PMID: 30799924 PMCID: PMC6369855 DOI: 10.2147/TCRM.S180170

Abstract

BACKGROUND: Recent studies have highlighted that Takotsubo syndrome (TTS), mimicking acute coronary syndrome (ACS), is associated with poor clinical outcome. TTS is associated with different repolarization disorders including ST-segment elevation. ST elevation myocardial infarction (STEMI) in ACS is associated with declined prognosis. However, the clinical and prognostic impact of ST-segment elevation on TTS remains lacking.

AIM: The aim of this study was to determine the short- and long-term prognostic impact of ST-segment elevation on TTS patients as compared with STEMI patients.

PATIENTS AND METHODS: Our institutional database constituted a consecutive cohort of 138 TTS patients and 138 ACS patients matched for age and sex. TTS patients (n=41) with ST-segment elevation were compared with ACS patients with ST-segment elevation (n=64).

RESULTS: Chest pain was significantly more documented in STEMI patients as compared with TTS patients (48.8% vs 78.1%;

CONCLUSION: Rates of the long-term mortality in TTS patients with ST elevations are comparable with STEMI patients.

Keywords: ST elevation; Takotsubo syndrome; coronary artery syndrome; prognosis

Conflict of interest statement

Disclosure The authors report no conflicts of interest in this work.

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