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Lopez J, Richardson E, Tiozzo E, et al. The effect of exercise training on disease progression, fitness, quality of life, and mental health in people living with HIV on antiretroviral therapy: a systematic review. J Clin Transl Res. 2015;1(3):129-139
Lopez, J., Richardson, E., Tiozzo, E., Lantigua, L., Martinez, C., Abreut, G., Prendergast, T., Atlas, S. E., Pangilinan, A. R., Ferris, S. M., Martinez, A. H., Konefal, J., Woolger, J., Ray, A. M., Simões, H. G., Campbell, C. S. G., & Lewis, J. E. (2015). The effect of exercise training on disease progression, fitness, quality of life, and mental health in people living with HIV on antiretroviral therapy: a systematic review. Journal of clinical and translational research, 1(3), 129-139.
Lopez, Johanna, et al. "The effect of exercise training on disease progression, fitness, quality of life, and mental health in people living with HIV on antiretroviral therapy: a systematic review." Journal of clinical and translational research vol. 1,3 (2015): 129-139.
Lopez J, Richardson E, Tiozzo E, Lantigua L, Martinez C, Abreut G, Prendergast T, Atlas SE, Pangilinan AR, Ferris SM, Martinez AH, Konefal J, Woolger J, Ray AM, Simões HG, Campbell CSG, Lewis JE. The effect of exercise training on disease progression, fitness, quality of life, and mental health in people living with HIV on antiretroviral therapy: a systematic review. J Clin Transl Res. 2015 Nov 30;1(3):129-139. eCollection 2015 Dec 30. PMID: 30873450; PMCID: PMC6410621.
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J Clin Transl Res. 2015 Nov 30;1(3):129-139. eCollection 2015 Dec 30.

The effect of exercise training on disease progression, fitness, quality of life, and mental health in people living with HIV on antiretroviral therapy: a systematic review.

Journal of clinical and translational research

Johanna Lopez, Erika Richardson, Eduard Tiozzo, Laura Lantigua, Camilo Martinez, George Abreut, Troy Prendergast, Steven E Atlas, Andrew R Pangilinan, Serena M Ferris, Ana H Martinez, Janet Konefal, Judi Woolger, Anna M Ray, Herbert G Simões, Carmen S G Campbell, John E Lewis

Affiliations

  1. Department of Psychiatry & Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL, United States.
  2. Department of Family Medicine, University of Miami Miller School of Medicine, Miami, FL, United States.
  3. Department of Medicine, University of Miami Miller School of Medicine, Miami, FL, United States.

PMID: 30873450 PMCID: PMC6410621

Abstract

BACKGROUND: Exercise has been associated with improvements in adverse physiological and psychological effects of long-term antiretroviral therapy (ART) in people living with HIV (PLWH).

AIM: To summarizes the findings on the effects of aerobic or resistance training alone or combined aerobic and resistance exercise training (CARET) on disease progression, fitness, physical functioning, mental health, and quality of life (QOL) in PLWH receiving ART. A systematic search of articles was performed in several databases, and 20 articles that met inclusion criteria were summarized.

RELEVANCE FOR PATIENTS: Aerobic exercise was associated with improvements in aerobic capacity, QOL, and depressive symptoms, while resistance training improved strength. CARET was related to improved aerobic fitness, strength, physical functioning, QOL, and self-efficacy. At least one of the exercise interventions resulted in improvements in CD4+ cell count and HIV RNA viral load. Moreover, another study showed that HIV-specific biomarkers remained unchanged in the exercise intervention group, while they significantly worsened in the non-exercise group. In general, in spite of their well-known benefits, exercise programs have not been extensively utilized or widely recognized as viable therapeutic treatment options for this patient population. Knowing the possible health benefits of increasing physical activity level is important to better recommend exercise programs. However, the prescription must be done carefully and on an individual basis. Additional studies investigating the efficiency and effectiveness of different exercise training regimens for PLWH are needed.

Keywords: HIV/AIDS; aerobic and resistance exercise training; general wellbeing; immune functioning

Conflict of interest statement

The authors declare that there are no conflicts of interest present.

References

  1. AIDS. 1999 Feb 4;13(2):231-9 - PubMed
  2. AIDS. 1999 Jul 30;13(11):1373-5 - PubMed
  3. AIDS. 2000 Mar 31;14(5):499-507 - PubMed
  4. Br J Sports Med. 2000 Aug;34(4):246-51 - PubMed
  5. J Appl Physiol (1985). 2001 Jan;90(1):133-8 - PubMed
  6. AIDS Care. 2001 Apr;13(2):197-208 - PubMed
  7. AIDS Patient Care STDS. 2001 Mar;15(3):159-67 - PubMed
  8. AIDS Clin Care. 1998 Jun;10(6):41-4 - PubMed
  9. AIDS. 2001 Apr 13;15(6):693-701 - PubMed
  10. AIDS. 2001 Oct 19;15(15):2049-51 - PubMed
  11. Diabetes Metab. 2002 Nov;28(5):397-404 - PubMed
  12. J Assoc Nurses AIDS Care. 2003 Jan-Feb;14(1):73-8 - PubMed
  13. Sex Transm Infect. 2003 Apr;79(2):137-41 - PubMed
  14. J Assoc Nurses AIDS Care. 2003 Mar-Apr;14(2):30-40 - PubMed
  15. AIDS Patient Care STDS. 2003 May;17(5):221-33 - PubMed
  16. AIDS. 2003 Apr;17 Suppl 1:S123-9 - PubMed
  17. J Int Assoc Physicians AIDS Care (Chic). 2002 Nov;1 Suppl 1:S1-15 - PubMed
  18. CMAJ. 2004 Jan 20;170(2):229-38 - PubMed
  19. Sports Med. 2004;34(8):487-99 - PubMed
  20. J Altern Complement Med. 2005 Dec;11(6):1085-92 - PubMed
  21. Med Sci Sports Exerc. 2006 Mar;38(3):411-7 - PubMed
  22. Arch Intern Med. 2006 Jun 12;166(11):1225-31 - PubMed
  23. Prim Care Companion J Clin Psychiatry. 2006;8(2):106 - PubMed
  24. Aust J Physiother. 2006;52(3):185-90 - PubMed
  25. Biol Res Nurs. 2007 Jan;8(3):177-85 - PubMed
  26. J Appl Physiol (1985). 2007 Aug;103(2):693-9 - PubMed
  27. Coll Antropol. 2006 Dec;30 Suppl 2:3-10 - PubMed
  28. AIDS Res Hum Retroviruses. 2008 Jan;24(1):15-23 - PubMed
  29. Qual Life Res. 2008 Apr;17(3):377-85 - PubMed
  30. AIDS Care. 2008 Oct;20(9):1066-74 - PubMed
  31. J Clin Endocrinol Metab. 2008 Oct;93(10):3860-9 - PubMed
  32. HIV Clin Trials. 2010 Sep-Oct;11(5):270-82 - PubMed
  33. Rev Bras Fisioter. 2010 Sep-Oct;14(5):390-5 - PubMed
  34. Ann Pharmacother. 2012 Feb;46(2):240-7 - PubMed
  35. Maturitas. 2013 Jan;74(1):89-94 - PubMed
  36. Neuropsychobiology. 2013;68(1):1-14 - PubMed
  37. Circulation. 2014 Jan 21;129(3):e28-e292 - PubMed
  38. Niger J Clin Pract. 2014 Sep-Oct;17(5):543-8 - PubMed
  39. Malawi Med J. 2015 Mar;27(1):5-9 - PubMed
  40. J Palliat Care. 1997 Summer;13(2):9-13 - PubMed
  41. Nurs Res. 1997 Nov-Dec;46(6):318-23 - PubMed
  42. Med Sci Sports Exerc. 1998 Jan;30(1):11-6 - PubMed
  43. N Engl J Med. 1998 Mar 26;338(13):853-60 - PubMed
  44. Am J Psychiatry. 1999 Jan;156(1):94-100 - PubMed

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