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Sparber F, LeibundGut-Landmann S. Interleukin-17 in Antifungal Immunity. Pathogens. 2019;8(2)doi: 10.3390/pathogens8020054.
Sparber, F., & LeibundGut-Landmann, S. (2019). Interleukin-17 in Antifungal Immunity. Pathogens (Basel, Switzerland), 8(2), . https://doi.org/10.3390/pathogens8020054
Sparber, Florian, and LeibundGut-Landmann, Salomé. "Interleukin-17 in Antifungal Immunity." Pathogens (Basel, Switzerland) vol. 8,2 (2019). doi: https://doi.org/10.3390/pathogens8020054
Sparber F, LeibundGut-Landmann S. Interleukin-17 in Antifungal Immunity. Pathogens. 2019 Apr 22;8(2). doi: 10.3390/pathogens8020054. PMID: 31013616; PMCID: PMC6630750.
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Pathogens. 2019 Apr 22;8(2). doi: 10.3390/pathogens8020054.

Interleukin-17 in Antifungal Immunity.

Pathogens (Basel, Switzerland)

Florian Sparber, Salomé LeibundGut-Landmann

Affiliations

  1. Section of Immunology, Vetsuisse Faculty, University of Zürich, Winterthurerstrasse 266a, CH-8057 Zürich, Switzerland. [email protected].
  2. Section of Immunology, Vetsuisse Faculty, University of Zürich, Winterthurerstrasse 266a, CH-8057 Zürich, Switzerland. [email protected].

PMID: 31013616 PMCID: PMC6630750 DOI: 10.3390/pathogens8020054

Abstract

The field of IL-17 biology has received much attention over the last decade owing to the pathogenic role of this cytokine in psoriasis and other autoinflammatory disorders and the successful implementation of IL-17-targeting therapies in patients suffering from these diseases. IL-17-mediated pathologies are contrasted by the important host beneficial effects of this cytokine. IL-17 is essential for regulating microbial colonization in barrier tissues. Rare congenital defects in the IL-17 pathway exemplify the relevance of IL-17 in protective immunity against the opportunistic fungal pathogen

Keywords: C. albicans; Interleukin-17; fungal commensals; fungal pathogens; host protection; immunopathology

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