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Liu Y, Zhao Y, Chen X. Bioengineering of Metal-organic Frameworks for Nanomedicine. Theranostics. 2019;9(11):3122-3133doi: 10.7150/thno.31918.
Liu, Y., Zhao, Y., & Chen, X. (2019). Bioengineering of Metal-organic Frameworks for Nanomedicine. Theranostics, 9(11), 3122-3133. https://doi.org/10.7150/thno.31918
Liu, Yuan, et al. "Bioengineering of Metal-organic Frameworks for Nanomedicine." Theranostics vol. 9,11 (2019): 3122-3133. doi: https://doi.org/10.7150/thno.31918
Liu Y, Zhao Y, Chen X. Bioengineering of Metal-organic Frameworks for Nanomedicine. Theranostics. 2019 May 18;9(11):3122-3133. doi: 10.7150/thno.31918. eCollection 2019. PMID: 31244945; PMCID: PMC6567971.
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Theranostics. 2019 May 18;9(11):3122-3133. doi: 10.7150/thno.31918. eCollection 2019.

Bioengineering of Metal-organic Frameworks for Nanomedicine.

Theranostics

Yuan Liu, Yanli Zhao, Xiaoyuan Chen

Affiliations

  1. Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland 20892, United States.
  2. Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore, 637371, Singapore.

PMID: 31244945 PMCID: PMC6567971 DOI: 10.7150/thno.31918

Abstract

Controlled structure, tunable porosity, and readily chemical functionalizability make metal-organic frameworks (MOFs) a powerful biomedical tool. Nanoscale MOF particles have been increasingly studied as drug carriers, bioimaging agents, and therapeutic agents due to their excellent physiochemical properties. In this review, we start with MOF as a nanocarrier for drug delivery, covering therapeutic MOF agents followed by a comprehensive discussion of surface bioengineering of MOF for improved biostability, biocompatibility, and targeted delivery. Finally, we detail the challenges and prospects of the future of MOF research for biomedical applications.

Keywords: Metal-organic frameworks; drug delivery; photodynamic therapy; surface engineering

Conflict of interest statement

Competing Interests: The authors have declared that no competing interest exists.

References

  1. Nat Mater. 2004 Dec;3(12):891-5 - PubMed
  2. J Immunol. 2005 Jun 15;174(12):7516-23 - PubMed
  3. Mol Cancer Ther. 2006 Aug;5(8):1909-17 - PubMed
  4. Biomaterials. 2008 Feb;29(4):487-96 - PubMed
  5. Blood. 2009 Jul 16;114(3):589-95 - PubMed
  6. Nat Mater. 2010 Feb;9(2):172-8 - PubMed
  7. Adv Drug Deliv Rev. 2011 Mar 18;63(3):136-51 - PubMed
  8. Angew Chem Int Ed Engl. 2010 Jul 19;49(31):5357-61 - PubMed
  9. J Am Chem Soc. 2011 Feb 16;133(6):1734-7 - PubMed
  10. Angew Chem Int Ed Engl. 2011 Apr 11;50(16):3696-700 - PubMed
  11. J Am Chem Soc. 2011 Aug 17;133(32):12664-74 - PubMed
  12. Chem Rev. 2012 Feb 8;112(2):1232-68 - PubMed
  13. Nat Chem. 2012 Feb 19;4(4):310-6 - PubMed
  14. Chem Rev. 2013 Apr 10;113(4):2842-62 - PubMed
  15. ACS Nano. 2013 Jun 25;7(6):5320-9 - PubMed
  16. Science. 2013 Aug 30;341(6149):1230444 - PubMed
  17. Chem Soc Rev. 2014 Feb 7;43(3):744-64 - PubMed
  18. Acc Chem Res. 2014 Feb 18;47(2):459-69 - PubMed
  19. ACS Nano. 2014 Mar 25;8(3):2812-9 - PubMed
  20. J Am Chem Soc. 2014 Apr 9;136(14):5181-4 - PubMed
  21. AAPS PharmSciTech. 2014 Aug;15(4):862-71 - PubMed
  22. J Am Chem Soc. 2014 May 21;136(20):7261-4 - PubMed
  23. J Am Chem Soc. 2014 Sep 10;136(36):12552-5 - PubMed
  24. Science. 2014 Oct 3;346(6205):1247390 - PubMed
  25. J Am Chem Soc. 2014 Dec 3;136(48):16712-5 - PubMed
  26. Nano Lett. 2015 Feb 11;15(2):842-8 - PubMed
  27. Inorg Chem. 2015 Mar 2;54(5):2185-92 - PubMed
  28. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2015 Sep-Oct;7(5):691-707 - PubMed
  29. Cancer Treat Rev. 2015 Jun;41(6):503-10 - PubMed
  30. Adv Mater. 2015 Jul 15;27(27):4075-80 - PubMed
  31. Small. 2015 Oct 7;11(37):4806-22 - PubMed
  32. Chem Commun (Camb). 2015 Nov 11;51(87):15752-5 - PubMed
  33. Nanoscale. 2015 Oct 14;7(38):16061-70 - PubMed
  34. Adv Mater. 2015 Dec 2;27(45):7372-8 - PubMed
  35. Angew Chem Int Ed Engl. 2015 Dec 1;54(49):14738-42 - PubMed
  36. J Am Chem Soc. 2015 Dec 2;137(47):14952-8 - PubMed
  37. Front Pharmacol. 2015 Dec 01;6:286 - PubMed
  38. J Am Chem Soc. 2016 Jan 27;138(3):962-8 - PubMed
  39. J Am Chem Soc. 2016 Mar 16;138(10):3518-25 - PubMed
  40. Nanoscale. 2016 Mar 28;8(12):6684-92 - PubMed
  41. Angew Chem Int Ed Engl. 2016 Apr 25;55(18):5477-82 - PubMed
  42. Nanomedicine (Lond). 2016 May;11(9):1169-85 - PubMed
  43. Biomaterials. 2016 Aug;97:1-9 - PubMed
  44. Theranostics. 2016 Jun 15;6(9):1440-52 - PubMed
  45. Int J Pharm. 2016 Sep 25;511(2):1042-7 - PubMed
  46. J Am Chem Soc. 2016 Sep 28;138(38):12502-10 - PubMed
  47. ACS Nano. 2016 Oct 25;10(10):9174-9182 - PubMed
  48. Nature. 2016 Nov 3;539(7627):76-80 - PubMed
  49. Chem Soc Rev. 2016 Nov 21;45(23):6488-6519 - PubMed
  50. Adv Healthc Mater. 2017 Jan;6(2):null - PubMed
  51. ACS Appl Mater Interfaces. 2017 Jan 25;9(3):2040-2051 - PubMed
  52. J Am Chem Soc. 2017 Feb 15;139(6):2359-2368 - PubMed
  53. Bioconjug Chem. 2017 Apr 19;28(4):1068-1075 - PubMed
  54. Biomaterials. 2017 Apr;123:172-183 - PubMed
  55. ACS Appl Mater Interfaces. 2017 Mar 1;9(8):6712-6724 - PubMed
  56. Bioconjug Chem. 2017 Apr 19;28(4):857-868 - PubMed
  57. ACS Nano. 2017 Apr 25;11(4):4247-4255 - PubMed
  58. Adv Mater. 2017 Jun;29(23): - PubMed
  59. J Am Chem Soc. 2017 Apr 26;139(16):5877-5882 - PubMed
  60. Chem Soc Rev. 2017 Jun 6;46(11):3386-3401 - PubMed
  61. J Am Chem Soc. 2017 Jul 26;139(29):9827-9830 - PubMed
  62. Angew Chem Int Ed Engl. 2017 Oct 23;56(44):13752-13756 - PubMed
  63. J Am Chem Soc. 2017 Oct 4;139(39):13804-13810 - PubMed
  64. J Am Chem Soc. 2017 Oct 25;139(42):15251-15258 - PubMed
  65. Chem Sci. 2017 Aug 1;8(8):5769-5780 - PubMed
  66. Chem Sci. 2017 Sep 1;8(9):6182-6187 - PubMed
  67. Nat Rev Mater. 2017;2:null - PubMed
  68. Nat Commun. 2017 Nov 14;8(1):1482 - PubMed
  69. Theranostics. 2017 Oct 13;7(18):4605-4617 - PubMed
  70. ACS Appl Mater Interfaces. 2018 Jan 24;10(3):2328-2337 - PubMed
  71. Angew Chem Int Ed Engl. 2018 Apr 23;57(18):4891-4896 - PubMed
  72. Angew Chem Int Ed Engl. 2018 Apr 23;57(18):4902-4906 - PubMed
  73. ACS Nano. 2018 Mar 27;12(3):2094-2105 - PubMed
  74. J Am Chem Soc. 2018 May 2;140(17):5678-5681 - PubMed
  75. J Am Chem Soc. 2018 May 2;140(17):5670-5673 - PubMed
  76. Angew Chem Int Ed Engl. 2018 Jun 25;57(26):7836-7840 - PubMed
  77. Chem Commun (Camb). 2018 May 22;54(42):5377-5380 - PubMed
  78. Angew Chem Int Ed Engl. 2018 Jul 9;57(28):8463-8467 - PubMed
  79. Adv Mater. 2018 Sep;30(37):e1707365 - PubMed
  80. Angew Chem Int Ed Engl. 2018 Jul 26;57(31):9790-9794 - PubMed
  81. Nat Commun. 2018 Jun 15;9(1):2351 - PubMed
  82. ACS Nano. 2018 Aug 28;12(8):7538-7545 - PubMed
  83. Angew Chem Int Ed Engl. 2019 Jan 14;58(3):670-680 - PubMed
  84. Theranostics. 2018 May 24;8(13):3461-3473 - PubMed
  85. Adv Drug Deliv Rev. 2018 Sep;134:65-78 - PubMed
  86. Theranostics. 2018 Jul 16;8(15):4086-4096 - PubMed
  87. Biomater Sci. 2018 Sep 25;6(10):2582-2590 - PubMed
  88. Theranostics. 2018 Jul 30;8(16):4332-4344 - PubMed
  89. Chem Sci. 2018 Jul 30;9(38):7505-7509 - PubMed
  90. Nanoscale. 2018 Dec 7;10(45):21369-21373 - PubMed
  91. Adv Mater. 2018 Dec 12;:e1803291 - PubMed
  92. Small. 2019 Jan;15(4):e1804131 - PubMed
  93. J Am Chem Soc. 2019 Feb 13;141(6):2215-2219 - PubMed
  94. J Am Chem Soc. 2019 Feb 13;141(6):2568-2576 - PubMed
  95. J Am Chem Soc. 2019 Mar 6;141(9):3782-3786 - PubMed
  96. Nat Biomed Eng. 2018 Aug;2(8):600-610 - PubMed

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