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Wu S, Tu R, Liang X. Patchy echogenicity of the liver in patients with chronic hepatitis B does not indicate poorer elasticity. Ultrasonography. 2019;38(4):327-335doi: 10.14366/usg.18071.
Wu, S., Tu, R., & Liang, X. (2019). Patchy echogenicity of the liver in patients with chronic hepatitis B does not indicate poorer elasticity. Ultrasonography (Seoul, Korea), 38(4), 327-335. https://doi.org/10.14366/usg.18071
Wu, Size, et al. "Patchy echogenicity of the liver in patients with chronic hepatitis B does not indicate poorer elasticity." Ultrasonography (Seoul, Korea) vol. 38,4 (2019): 327-335. doi: https://doi.org/10.14366/usg.18071
Wu S, Tu R, Liang X. Patchy echogenicity of the liver in patients with chronic hepatitis B does not indicate poorer elasticity. Ultrasonography. 2019 Oct;38(4):327-335. doi: 10.14366/usg.18071. Epub 2019 Feb 14. PMID: 31302950; PMCID: PMC6769196.
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Ultrasonography. 2019 Oct;38(4):327-335. doi: 10.14366/usg.18071. Epub 2019 Feb 14.

Patchy echogenicity of the liver in patients with chronic hepatitis B does not indicate poorer elasticity.

Ultrasonography (Seoul, Korea)

Size Wu, Rong Tu, Xian Liang

Affiliations

  1. Department of Ultrasound, The First Affiliated Hospital of Hainan Medical University, Haikou, China.
  2. Department of Radiology, The First Affiliated Hospital of Hainan Medical University, Haikou, China.

PMID: 31302950 PMCID: PMC6769196 DOI: 10.14366/usg.18071

Abstract

PURPOSE: This study was conducted to investigate whether the presence of patchy echogenicity in the liver of patients with chronic hepatitis B (CHB) is predictive of liver stiffness.

METHODS: A total of 200 CHB patients with and without patchy echogenicity of the liver were assigned to two groups, with 100 patients in each group, and 32 of them underwent liver biopsy. Additionally, 80 healthy subjects, 100 inactive HBV carriers, and 100 patients with decompensated hepatic cirrhosis were assigned to the control groups. Laboratory tests and clinical data were collected, and shear wave velocity (SWV) of the liver was measured for all 480 subjects.

RESULTS: The median SWV in patients with a normal liver, inactive hepatitis B virus carriers, CHB patients with and without patchy echogenicity, and decompensated hepatic cirrhosis were 1.07 m/sec, 1.08 m/sec, 1.16 m/sec, 1.16 m/sec, and 2.02 m/sec, respectively; there was no significant difference in SWV values between CHB patients with patchy echogenicity and those without patchy echogenicity. Furthermore, among CHB patients with and without patchy echogenicity, no significant difference in SWV was found according to fibrosis stage.

CONCLUSION: The presence of patchy echogenicity of the liver does not indicate a higher degree of liver stiffness.

Keywords: Hepatitis B, chronic; Patchy echogenicity of the liver; Point shear wave elastography; Shear wave velocity; Ultrasonography

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