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Meyer HJ, Hamerla G, Leifels L, et al. Histogram analysis parameters derived from DCE-MRI in head and neck squamous cell cancer - Associations with microvessel density. Eur J Radiol. 2019;120:108669doi: 10.1016/j.ejrad.2019.108669.
Meyer, H. J., Hamerla, G., Leifels, L., Höhn, A. K., & Surov, A. (2019). Histogram analysis parameters derived from DCE-MRI in head and neck squamous cell cancer - Associations with microvessel density. European journal of radiology, 120108669. https://doi.org/10.1016/j.ejrad.2019.108669
Meyer, Hans-Jonas, et al. "Histogram analysis parameters derived from DCE-MRI in head and neck squamous cell cancer - Associations with microvessel density." European journal of radiology vol. 120 (2019): 108669. doi: https://doi.org/10.1016/j.ejrad.2019.108669
Meyer HJ, Hamerla G, Leifels L, Höhn AK, Surov A. Histogram analysis parameters derived from DCE-MRI in head and neck squamous cell cancer - Associations with microvessel density. Eur J Radiol. 2019 Nov;120:108669. doi: 10.1016/j.ejrad.2019.108669. Epub 2019 Sep 14. PMID: 31542700.
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Eur J Radiol. 2019 Nov;120:108669. doi: 10.1016/j.ejrad.2019.108669. Epub 2019 Sep 14.

Histogram analysis parameters derived from DCE-MRI in head and neck squamous cell cancer - Associations with microvessel density.

European journal of radiology

Hans-Jonas Meyer, Gordian Hamerla, Leonard Leifels, Anne Kathrin Höhn, Alexey Surov

Affiliations

  1. Department of Diagnostic and Interventional Radiology, University of Leipzig, Leipzig, 04103, Germany. Electronic address: [email protected].
  2. Department of Diagnostic and Interventional Radiology, University of Leipzig, Leipzig, 04103, Germany.
  3. Department of Pathology, University of Leipzig, Leipzig, Germany;c Department of Diagnostic and Interventional Radiology, Ulm University Medical Center, Albert-Einstein-Allee 23, 89081 Ulm, Germany.
  4. Department of Diagnostic and Interventional Radiology, University of Leipzig, Leipzig, 04103, Germany; Department of Diagnostic and Interventional Radiology, Ulm University Medical Center, Albert-Einstein-Allee 23, 89081 Ulm, Germany.

PMID: 31542700 DOI: 10.1016/j.ejrad.2019.108669

Abstract

PURPOSE: DCE MRI is a functional imaging modality, which is widely acknowledged to be linked to microvessel density in tissues. Therefore, it might be able to predict vessels in tumors. The present study sought to elucidate possible associations between microvessel density and histogram parameters in head and neck squamous cell carcinomas (HNSCC).

METHOD: 30 patients with histologically proven HNSCC were included in the study. DCE MRI was performed with a 3 T MRI and histogram analysis was calculated with a whole lesion measurement. In every case microvessel density was estimated with CD105 stained specimens.

RESULTS: Median derived from K

CONCLUSIONS: Histogram parameters derived from K

Copyright © 2019 Elsevier B.V. All rights reserved.

Keywords: DCE MRI; HNSCC; MRI; MVD

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