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Front Microbiol. 2019 Aug 27;10:1954. doi: 10.3389/fmicb.2019.01954. eCollection 2019.

A Comprehensive Antimicrobial Activity Evaluation of the Recombinant Microcin J25 Against the Foodborne Pathogens .

Frontiers in microbiology

Haitao Yu, Ning Li, Xiangfang Zeng, Lu Liu, Yuming Wang, Gang Wang, Shuang Cai, Shuo Huang, Xiuliang Ding, Qinglong Song, Shiyan Qiao

Affiliations

  1. State Key Laboratory of Animal Nutrition, China Agricultural University, Beijing, China.
  2. Ministry of Agriculture and Rural Affairs Feed Industry Centre, China Agricultural University, Beijing, China.
  3. Beijing Key Laboratory of Bio-Feed Additives, Beijing, China.

PMID: 31507565 PMCID: PMC6718478 DOI: 10.3389/fmicb.2019.01954

Abstract

Natural microcin J25 (MccJ25) represent promising alternatives to traditional antibiotics for the treatment of drug-resistant infections. However, little is known about the antibacterial activity of recombinant MccJ25 against foodborne pathogens. Here, the activity of recombinant MccJ25 was examined using a matrix of conditions in order to assess the efficacy of recombinant MccJ25 as a mitigation against foodborne pathogens, such as

Keywords: Escherichia coli O157:H7; Salmonella; antimicrobial activity; biological environments; mitigation; recombinant microcin J25; stability

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