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Woo J, Yang H, Yoon M, et al. 3-Carene, a Phytoncide from Pine Tree Has a Sleep-enhancing Effect by Targeting the GABA. Exp Neurobiol. 2019;28(5):593-601doi: 10.5607/en.2019.28.5.593.
Woo, J., Yang, H., Yoon, M., Gadhe, C. G., Pae, A. N., Cho, S., & Lee, C. J. (2019). 3-Carene, a Phytoncide from Pine Tree Has a Sleep-enhancing Effect by Targeting the GABA. Experimental neurobiology, 28(5), 593-601. https://doi.org/10.5607/en.2019.28.5.593
Woo, Junsung, et al. "3-Carene, a Phytoncide from Pine Tree Has a Sleep-enhancing Effect by Targeting the GABA." Experimental neurobiology vol. 28,5 (2019): 593-601. doi: https://doi.org/10.5607/en.2019.28.5.593
Woo J, Yang H, Yoon M, Gadhe CG, Pae AN, Cho S, Lee CJ. 3-Carene, a Phytoncide from Pine Tree Has a Sleep-enhancing Effect by Targeting the GABA. Exp Neurobiol. 2019 Oct 31;28(5):593-601. doi: 10.5607/en.2019.28.5.593. PMID: 31698551; PMCID: PMC6844839.
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Exp Neurobiol. 2019 Oct 31;28(5):593-601. doi: 10.5607/en.2019.28.5.593.

3-Carene, a Phytoncide from Pine Tree Has a Sleep-enhancing Effect by Targeting the GABA.

Experimental neurobiology

Junsung Woo, Hyejin Yang, Minseok Yoon, Changdev G Gadhe, Ae Nim Pae, Suengmok Cho, C Justin Lee

Affiliations

  1. Center for Neuroscience, Korea Institute of Science and Technology (KIST), Department of Neuroscience, Division of Bio- Medical Science & Technology, KIST School, Korea University of Science and Technology, Seoul 02792, Korea.
  2. Research Division of Food Functionality, Korea Food Research Institute, Wanju 55365, Korea.
  3. Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul 02791, Korea.
  4. Department of Food Science and Technology, Pukyong National University, Busan 48513, Korea.
  5. Center for Cognition and Sociality, Institute for Basic Science, Daejeon 34126, Korea.

PMID: 31698551 PMCID: PMC6844839 DOI: 10.5607/en.2019.28.5.593

Abstract

3-Carene, a bicyclic monoterpene, is one of the major components of the pine tree essential oils. It has been reported that, in addition to its known properties as a phytoncide, 3-carene has anti-inflammatory, antimicrobial, and anxiolytic effects. We have previously demonstrated that α-pinene, the major component of pine tree, has a hypnotic effect through GABA

Keywords: 3-carene; GABAA-BZD receptor; Phytoncide; Sleep

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