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Dong M, Yang Z, Fang H, et al. Aging Attenuates Cardiac Contractility and Affects Therapeutic Consequences for Myocardial Infarction. Aging Dis. 2020;11(2):365-376doi: 10.14336/AD.2019.0522.
Dong, M., Yang, Z., Fang, H., Xiang, J., Xu, C., Zhou, Y., Wu, Q., & Liu, J. (2020). Aging Attenuates Cardiac Contractility and Affects Therapeutic Consequences for Myocardial Infarction. Aging and disease, 11(2), 365-376. https://doi.org/10.14336/AD.2019.0522
Dong, Ming, et al. "Aging Attenuates Cardiac Contractility and Affects Therapeutic Consequences for Myocardial Infarction." Aging and disease vol. 11,2 (2020): 365-376. doi: https://doi.org/10.14336/AD.2019.0522
Dong M, Yang Z, Fang H, Xiang J, Xu C, Zhou Y, Wu Q, Liu J. Aging Attenuates Cardiac Contractility and Affects Therapeutic Consequences for Myocardial Infarction. Aging Dis. 2020 Mar 09;11(2):365-376. doi: 10.14336/AD.2019.0522. eCollection 2020 Apr. PMID: 32257547; PMCID: PMC7069457.
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Aging Dis. 2020 Mar 09;11(2):365-376. doi: 10.14336/AD.2019.0522. eCollection 2020 Apr.

Aging Attenuates Cardiac Contractility and Affects Therapeutic Consequences for Myocardial Infarction.

Aging and disease

Ming Dong, Ziyi Yang, Hongcheng Fang, Jiaqing Xiang, Cong Xu, Yanqing Zhou, Qianying Wu, Jie Liu

Affiliations

  1. 1Department of Pathophysiology, Guangdong Key Laboratory of Genome Stability and Human Disease Prevention, Shenzhen University Health Science Center, Guangdong, China.
  2. 2Shenzhen Shajing Hospital, Affiliated of Guangzhou Medical University, Shenzhen, Guangdong, China.

PMID: 32257547 PMCID: PMC7069457 DOI: 10.14336/AD.2019.0522

Abstract

Cardiac function of the human heart changes with age. The age-related change of systolic function is subtle under normal conditions, but abrupt under stress or in a pathogenesis state. Aging decreases the cardiac tolerance to stress and increases susceptibility to ischemia, which caused by aging-induced Ca

Copyright: © 2020 Dong et al.

Keywords: aging; cardiac contractility; cardiac ischemia; cardiac ischemia therapy; ischemia and reperfusion injury

References

  1. Am J Physiol. 1993 May;264(5 Pt 2):H1609-14 - PubMed
  2. J Proteomics. 2012 Sep 18;75(17):5386-95 - PubMed
  3. Nat Commun. 2018 Jul 2;9(1):2560 - PubMed
  4. Cell Physiol Biochem. 2017;44(3):1011-1023 - PubMed
  5. J Drug Target. 2018 Dec;26(10):895-904 - PubMed
  6. Basic Res Cardiol. 2011 Nov;106(6):1173-91 - PubMed
  7. J Mol Cell Cardiol. 2008 Oct;45(4):567-81 - PubMed
  8. Mol Cell Biochem. 2011 Jan;347(1-2):209-15 - PubMed
  9. Circ Res. 2014 Jan 3;114(1):101-8 - PubMed
  10. Sci Transl Med. 2018 Feb 7;10(427): - PubMed
  11. Med Sci Sports Exerc. 2018 Mar;50(3):494-501 - PubMed
  12. Am J Physiol Heart Circ Physiol. 2004 Nov;287(5):H2132-7 - PubMed
  13. J Physiol. 2017 Oct 1;595(19):6249-6262 - PubMed
  14. Circ Res. 2008 Mar 14;102(5):571-80 - PubMed
  15. Stem Cells. 2014 Sep;32(9):2373-85 - PubMed
  16. Cardiovasc Res. 2016 Jul 15;111(2):142-53 - PubMed
  17. Exp Gerontol. 2008 Oct;43(10):909-18 - PubMed
  18. Am J Pathol. 2015 Mar;185(3):631-42 - PubMed
  19. BMC Med Imaging. 2013 Feb 07;13:6 - PubMed
  20. Clin Epigenetics. 2016 Jun 03;8:64 - PubMed
  21. Lancet. 2011 Nov 26;378(9806):1847-57 - PubMed
  22. Circulation. 1999 Dec 7;100(23):2308-11 - PubMed
  23. Antioxid Redox Signal. 2013 Mar 20;18(9):1063-77 - PubMed
  24. Exp Aging Res. 2005 Jan-Mar;31(1):55-67 - PubMed
  25. PLoS One. 2018 Apr 27;13(4):e0196739 - PubMed
  26. Stem Cell Rev Rep. 2018 Aug;14(4):612-625 - PubMed
  27. Int J Mol Sci. 2018 Jan 31;19(2): - PubMed
  28. Nat Rev Cardiol. 2014 May;11(5):255-65 - PubMed
  29. Nature. 2017 Aug 3;548(7665):52-57 - PubMed
  30. Physiol Rep. 2017 Nov;5(20): - PubMed
  31. Geroscience. 2017 Feb;39(1):7-18 - PubMed
  32. Endocrine. 2005 Mar;26(2):127-37 - PubMed
  33. J Mol Cell Cardiol. 2016 Apr;93:175-85 - PubMed
  34. J Geriatr Cardiol. 2015 Sep;12(5):569-74 - PubMed
  35. Cell Death Dis. 2014 Dec 18;5:e1573 - PubMed
  36. J Cardiovasc Transl Res. 2018 Oct;11(5):420-428 - PubMed
  37. Lancet. 2016 Mar 19;387(10024):1178-86 - PubMed
  38. Cardiovasc Res. 2019 Jan 1;115(1):230-242 - PubMed
  39. J Mol Cell Cardiol. 2014 Dec;77:102-12 - PubMed
  40. Comp Biochem Physiol A Mol Integr Physiol. 2002 Aug;132(4):699-721 - PubMed
  41. Circ Res. 2016 Jan 22;118(2):279-95 - PubMed
  42. J Am Coll Cardiol. 2008 Apr 8;51(14):1384-92 - PubMed
  43. Exp Gerontol. 2008 Apr;43(4):296-306 - PubMed
  44. Aging Cell. 2015 Aug;14(4):644-58 - PubMed
  45. Mech Ageing Dev. 2017 Sep;166:6-15 - PubMed
  46. Annu Rev Physiol. 2018 Feb 10;80:27-48 - PubMed
  47. Cardiovasc Res. 2017 Mar 1;113(3):343-353 - PubMed
  48. Stem Cell Reports. 2014 May 08;2(5):606-19 - PubMed
  49. J Mol Cell Cardiol. 2014 Jul;72:138-45 - PubMed
  50. Nat Med. 2018 Aug;24(8):1246-1256 - PubMed
  51. Mech Ageing Dev. 2008 Jun;129(6):304-12 - PubMed
  52. Am J Physiol Heart Circ Physiol. 2012 Feb 1;302(3):H855-63 - PubMed
  53. Eur Heart J. 2003 Dec;24(24):2213-20 - PubMed
  54. Biomed Res Int. 2014;2014:615312 - PubMed
  55. Mech Ageing Dev. 2001 Jul 31;122(10):1049-58 - PubMed
  56. Cardiovasc Ultrasound. 2012 May 28;10:22 - PubMed
  57. Clin Exp Pharmacol Physiol. 2010 Jan;37(1):1-7 - PubMed
  58. Circulation. 2017 Jul 11;136(2):200-214 - PubMed
  59. Circ J. 2011;75(9):2151-9 - PubMed
  60. Proteomics. 2008 Jun;8(12):2543-55 - PubMed
  61. J Thorac Cardiovasc Surg. 2010 May;139(5):1286-94, 1294.e1-2 - PubMed
  62. J Am Coll Cardiol. 2015 Jan 20;65(2):125-32 - PubMed
  63. Cardiovasc Res. 2010 Nov 1;88(2):334-43 - PubMed
  64. Circ Res. 2011 Mar 4;108(5):555-65 - PubMed
  65. Science. 2006 May 19;312(5776):1059-63 - PubMed
  66. Eur Heart J. 2015 Feb 7;36(6):353-68a - PubMed
  67. J Mol Cell Cardiol. 2000 Nov;32(11):2075-82 - PubMed
  68. J Am Coll Cardiol. 2004 Feb 4;43(3):346-52 - PubMed
  69. J Cell Mol Med. 2012 Jan;16(1):83-95 - PubMed
  70. Stem Cells Int. 2018 Mar 29;2018:9308301 - PubMed
  71. Circulation. 2014 Jan 21;129(3):346-58 - PubMed
  72. J Mol Cell Cardiol. 2005 Feb;38(2):241-4 - PubMed
  73. Cardiovasc Res. 2016 Jul 1;111(1):34-43 - PubMed
  74. Nature. 2013 Mar 7;495(7439):107-10 - PubMed
  75. J Am Soc Echocardiogr. 2004 Feb;17(2):132-8 - PubMed
  76. Am J Physiol Heart Circ Physiol. 2014 Jul 15;307(2):H252-8 - PubMed
  77. Aging Cell. 2017 Oct;16(5):943-955 - PubMed
  78. Circ Res. 2003 Oct 3;93(7):604-13 - PubMed
  79. Circulation. 2014 Mar 11;129(10):1139-51 - PubMed
  80. Aging Dis. 2012 Feb;3(1):130-40 - PubMed
  81. Circulation. 2011 Jul 19;124(3):304-13 - PubMed
  82. Circulation. 2000 Feb 22;101(7):790-6 - PubMed
  83. Exp Physiol. 2005 Jul;90(4):527-34 - PubMed
  84. PLoS One. 2016 Sep 12;11(9):e0162632 - PubMed
  85. Circ Res. 2018 Oct 26;123(10):e21-e31 - PubMed
  86. Am J Hypertens. 2003 Jun;16(6):473-7 - PubMed
  87. Heart Rhythm. 2018 May;15(5):752-760 - PubMed
  88. Free Radic Biol Med. 2015 Jun;83:115-28 - PubMed
  89. Antioxid Redox Signal. 2012 Jun 15;16(12):1492-526 - PubMed
  90. FASEB J. 2017 Sep;31(9):4153-4167 - PubMed
  91. Mol Cell. 2018 Sep 20;71(6):882-895 - PubMed
  92. J Pharmacol Sci. 2018 Apr;136(4):212-217 - PubMed
  93. Eur Heart J. 2017 Jan 14;38(3):201-211 - PubMed
  94. Arterioscler Thromb Vasc Biol. 2010 Nov;30(11):2301-9 - PubMed
  95. Card Fail Rev. 2017 Nov;3(2):79-82 - PubMed
  96. Nat Rev Cardiol. 2018 Oct;15(10):585-600 - PubMed
  97. Circulation. 2012 Nov 27;126(22):2575-88 - PubMed
  98. Exp Gerontol. 2018 Sep;110:172-181 - PubMed
  99. Eur J Echocardiogr. 2010 Mar;11(2):176-83 - PubMed
  100. Am J Physiol Heart Circ Physiol. 2006 Jan;290(1):H304-11 - PubMed
  101. Rev Bras Cir Cardiovasc. 2007 Oct-Dec;22(4):476-83 - PubMed
  102. Front Physiol. 2017 Jan 30;8:23 - PubMed
  103. Curr Pharm Des. 2013;19(9):1710-9 - PubMed
  104. PLoS Genet. 2013 Mar;9(3):e1003368 - PubMed
  105. Pharm Biol. 2017 Dec;55(1):1144-1148 - PubMed
  106. Heart Fail Clin. 2012 Jan;8(1):143-64 - PubMed

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