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AAS Open Res. 2019 Aug 13;2:17. doi: 10.12688/aasopenres.12972.2. eCollection 2019.

Risk assessment for the implementation of controlled human .

AAS open research

Jan Pieter Koopman, Moses Egesa, Anne Wajja, Moses Adriko, Jacent Nassuuna, Gyaviira Nkurunungi, Emmanuella Driciru, Gijsbert van Willigen, Stephen Cose, Maria Yazdanbakhsh, Pontiano Kaleebu, Narcis Kabatereine, Edridah Tukahebwa, Meta Roestenberg, Alison M Elliott

Affiliations

  1. Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands.
  2. Uganda Virus Research Institute, Entebbe, Uganda.
  3. Medical Research Council/Uganda Virus Research Institute and London School of Hygiene & Tropical Medicine Uganda Research Unit, Entebbe, Uganda.
  4. Vector Control Division, Ministry of Health of Uganda, Kampala, Uganda.
  5. Department of Health, Safety and the Environment, Leiden University Medical Center, Leiden, The Netherlands.
  6. Clinical Research Department, London School of Hygiene & Tropical Medicine, London, UK.

PMID: 31819922 PMCID: PMC6901351 DOI: 10.12688/aasopenres.12972.2

Abstract

Schistosomiasis is a parasitic infection highly prevalent in sub-Saharan Africa, and a significant cause of morbidity; it is a priority for vaccine development. A controlled human infection model for

Copyright: © 2019 Koopman JP et al.

Keywords: Controlled Human Infection Studies; Schistosoma mansoni; Uganda; risk assessment

Conflict of interest statement

Competing interests: The authors have declared no personal financial competing interests. However, we are working collaboratively to develop the CHI-S for implementation in Uganda, and therefore have

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