Display options
Cite
Liang M, Wang Z, Li Y, et al. Purkinje Fibers in Canine False Tendons: New Anatomical and Electrophysiological Findings. Cardiol Res Pract. 2020;2020:8156928doi: 10.1155/2020/8156928.
Liang, M., Wang, Z., Li, Y., Liang, Y., Zhang, Y., Rong, J., Lv, Y., Zhang, Q., Yang, G., Sun, M., Wang, J., Li, S., Wang, X., & Han, Y. (2020). Purkinje Fibers in Canine False Tendons: New Anatomical and Electrophysiological Findings. Cardiology research and practice, 20208156928. https://doi.org/10.1155/2020/8156928
Liang, Ming, et al. "Purkinje Fibers in Canine False Tendons: New Anatomical and Electrophysiological Findings." Cardiology research and practice vol. 2020 (2020): 8156928. doi: https://doi.org/10.1155/2020/8156928
Liang M, Wang Z, Li Y, Liang Y, Zhang Y, Rong J, Lv Y, Zhang Q, Yang G, Sun M, Wang J, Li S, Wang X, Han Y. Purkinje Fibers in Canine False Tendons: New Anatomical and Electrophysiological Findings. Cardiol Res Pract. 2020 Jun 15;2020:8156928. doi: 10.1155/2020/8156928. eCollection 2020. PMID: 32612855; PMCID: PMC7312736.
Copy Download .nbib Format: NLM
Share it on

Cardiol Res Pract. 2020 Jun 15;2020:8156928. doi: 10.1155/2020/8156928. eCollection 2020.

Purkinje Fibers in Canine False Tendons: New Anatomical and Electrophysiological Findings.

Cardiology research and practice

Ming Liang, Zulu Wang, Yi Li, Yanchun Liang, Yuji Zhang, Jingjing Rong, Yang Lv, Qi Zhang, Guitang Yang, Mingyu Sun, Junqi Wang, Sainan Li, Xunzhang Wang, Yaling Han

Affiliations

  1. Department of Cardiology, General Hospital of Northern Theater Command, Shenyang 110840, China.
  2. Heart Rhythm Center, The Heart Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA.

PMID: 32612855 PMCID: PMC7312736 DOI: 10.1155/2020/8156928

Abstract

INTRODUCTION: Purkinje system and false tendons (FTs) are related to ventricular arrhythmia, but the association between Purkinje fibers and FTs is not clear. This study investigated the associations of anatomical and electrophysiological characteristics between Purkinje fibers and FTs.

METHODS AND RESULTS: We optimized the protocol of Lugol's iodine solution staining of Purkinje fibers to study the anatomical structure and originated a novel electrophysiological mapping method, named the direct visual mapping (DVM) method, to study the electrophysiological characteristics. By using the above-mentioned innovations in 12 dogs, we found the following. (1) There was no Purkinje fiber found 0.5 cm-1.0 cm below the valve annulus or on the leaflets or chordae tendineae of the mitral valve or adjacent to the top 1/3 of the papillary muscle. (2) Purkinje fibers existed in all FTs, including smaller and tiny FTs. (3) The Purkinje fibers contained in the FTs extended from the proximal to the distal end, and their electrophysiological characteristics were similar to the fibers on the endocardium, including anterograde, retrograde, and decremental conduction and automaticity.

CONCLUSIONS: Purkinje fibers are commonly found in FTs. The electrophysiological characteristics of the Purkinje fibers contained in FTs are similar to the fibers on the endocardium. FTs might have an anatomical and electrophysiological basis for ventricular arrhythmia.

Copyright © 2020 Ming Liang et al.

Conflict of interest statement

The authors declare that there are no conflicts of interest regarding the publication of this paper.

References

  1. Pacing Clin Electrophysiol. 2009 Mar;32(3):283-5 - PubMed
  2. J Arrhythm. 2015 Oct;31(5):261-7 - PubMed
  3. J Cardiovasc Dev Dis. 2016 Apr 05;3(2): - PubMed
  4. Circ Arrhythm Electrophysiol. 2016 Sep;9(9): - PubMed
  5. World J Clin Cases. 2020 Jan 26;8(2):325-330 - PubMed
  6. Br Heart J. 1984 Dec;52(6):641-7 - PubMed
  7. Clin Anat. 2003 Sep;16(5):389-95 - PubMed
  8. Acta Cardiol. 1985;40(2):229-35 - PubMed
  9. Rev Port Cardiol. 1992 Dec;11(12):1125-31 - PubMed
  10. J Cell Biol. 1973 Jul;58(1):1-10 - PubMed
  11. Europace. 2012 Dec;14(12):1687-95 - PubMed
  12. Int J Cardiol. 1985 Jan;7(1):13-20 - PubMed
  13. Pediatr Neonatol. 2011 Oct;52(5):279-86 - PubMed
  14. Circulation. 2002 Jan 29;105(4):462-9 - PubMed
  15. Minerva Cardioangiol. 1992 Oct;40(10):353-8 - PubMed
  16. Pacing Clin Electrophysiol. 2011 May;34(5):624-50 - PubMed
  17. Heart Rhythm. 2014 Feb;11(2):321-4 - PubMed
  18. J Cardiovasc Electrophysiol. 2001 Aug;12(8):968-72 - PubMed
  19. J Am Coll Cardiol. 1988 Oct;12(4):910-4 - PubMed
  20. J Am Coll Cardiol. 2000 Sep;36(3):811-23 - PubMed
  21. Am J Cardiol. 1989 Nov 15;64(18):1217-20 - PubMed

Publication Types