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Park S, Kim M, Zhu J, et al. Inflammation suppression prevents tumor cell proliferation in a mouse model of thyroid cancer. Am J Cancer Res. 2020;10(6):1857-1870
Park, S., Kim, M., Zhu, J., Lee, W. K., Altan-Bonnet, G., Meltzer, P., & Cheng, S. Y. (2020). Inflammation suppression prevents tumor cell proliferation in a mouse model of thyroid cancer. American journal of cancer research, 10(6), 1857-1870.
Park, Sunmi, et al. "Inflammation suppression prevents tumor cell proliferation in a mouse model of thyroid cancer." American journal of cancer research vol. 10,6 (2020): 1857-1870.
Park S, Kim M, Zhu J, Lee WK, Altan-Bonnet G, Meltzer P, Cheng SY. Inflammation suppression prevents tumor cell proliferation in a mouse model of thyroid cancer. Am J Cancer Res. 2020 Jun 01;10(6):1857-1870. eCollection 2020. PMID: 32642296; PMCID: PMC7339265.
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Am J Cancer Res. 2020 Jun 01;10(6):1857-1870. eCollection 2020.

Inflammation suppression prevents tumor cell proliferation in a mouse model of thyroid cancer.

American journal of cancer research

Sunmi Park, Minjun Kim, Jack Zhu, Woo Kyung Lee, Grégoire Altan-Bonnet, Paul Meltzer, Sheue-Yann Cheng

Affiliations

  1. Laboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health Bethesda, MD 20892, Maryland, USA.
  2. Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health Bethesda, MD 20892, Maryland, USA.
  3. Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health Bethesda, MD 20892, Maryland, USA.

PMID: 32642296 PMCID: PMC7339265

Abstract

The incidence of thyroid cancer, the most frequent endocrine neoplasia, is rapidly increasing. Significant progress has recently been made in the identification of genetic lesions in thyroid cancer; however, whether inflammation contributes to thyroid cancer progression remains unknown. Using a mouse model of aggressive follicular thyroid cancer (FTC;

AJCR Copyright © 2020.

Keywords: CSF1R inhibitors thyroid cancer; Inflammation; colony-stimulating factor 1 receptor; monocytes; mouse model; pexidartinib (PLX-3397)

Conflict of interest statement

None.

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