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Zhang M, Zhou J, Yang LD, et al. [Interference of Exogenous Insulin on Insulin Detection Test by Electrochemiluminescence Immunoassay]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2018;49(6):924-928
Zhang, M., Zhou, J., Yang, L. D., Gui, X. M., Huang, J., Luo, K. H., & Huang, H. J. (2018). [Interference of Exogenous Insulin on Insulin Detection Test by Electrochemiluminescence Immunoassay]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 49(6), 924-928.
Zhang, Mei, et al. "[Interference of Exogenous Insulin on Insulin Detection Test by Electrochemiluminescence Immunoassay]." Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition vol. 49,6 (2018): 924-928.
Zhang M, Zhou J, Yang LD, Gui XM, Huang J, Luo KH, Huang HJ. [Interference of Exogenous Insulin on Insulin Detection Test by Electrochemiluminescence Immunoassay]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2018 Nov;49(6):924-928. Chinese. PMID: 32677406.
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Sichuan Da Xue Xue Bao Yi Xue Ban. 2018 Nov;49(6):924-928.

[Interference of Exogenous Insulin on Insulin Detection Test by Electrochemiluminescence Immunoassay].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition

[Article in Chinese]
Mei Zhang, Jun Zhou, Li-Dan Yang, Xue-Mei Gui, Jun Huang, Kai-Hong Luo, Heng-Jian Huang

Affiliations

  1. Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.

PMID: 32677406

Abstract

OBJECTIVE: To explore the interference of exogenous insulin therapy on insulin detection test by electrochemical luminescence immunoassay (ECLIA).

METHODS: Insulin level was determined by ECLIA. According to the requirements of EP7-A2 of American Society for Clinical Laboratory Standards Institute Standards, paired difference experiment was conducted to evaluate the interference of 8 kinds of exogenous insulin on insulin detection, dose effect experiment was conducted to determine the relationship between exogenous insulin concentration and interference degree.

RESULTS: When the interfering substance concentrations were ≤250 μU/mL, Gansulin N

CONCLUSIONS: The use of different exogenous insulin may have different interference on insulin measurement, which need laboratorians and physicians notice to avoid misdiagnosis.

Copyright© by Editorial Board of Journal of Sichuan University (Medical Science Edition).

Keywords: Electrochemiluminescence immunoassay; Exogenous insulin; Interference test

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