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Ye H, Jin C, Li X, et al. OCT-Angiography Comparison between Obstructive Sleep Apnea Children and Normal Subjects in China. Curr Eye Res. 2020;46(3):355-360doi: 10.1080/02713683.2020.1801757.
Ye, H., Jin, C., Li, X., Zhao, L., Li, Y., & Qiao, T. (2021). OCT-Angiography Comparison between Obstructive Sleep Apnea Children and Normal Subjects in China. Current eye research, 46(3), 355-360. https://doi.org/10.1080/02713683.2020.1801757
Ye, Haiyun, et al. "OCT-Angiography Comparison between Obstructive Sleep Apnea Children and Normal Subjects in China." Current eye research vol. 46,3 (2021): 355-360. doi: https://doi.org/10.1080/02713683.2020.1801757
Ye H, Jin C, Li X, Zhao L, Li Y, Qiao T. OCT-Angiography Comparison between Obstructive Sleep Apnea Children and Normal Subjects in China. Curr Eye Res. 2021 Mar;46(3):355-360. doi: 10.1080/02713683.2020.1801757. Epub 2020 Aug 11. PMID: 32730713.
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Curr Eye Res. 2021 Mar;46(3):355-360. doi: 10.1080/02713683.2020.1801757. Epub 2020 Aug 11.

OCT-Angiography Comparison between Obstructive Sleep Apnea Children and Normal Subjects in China.

Current eye research

Haiyun Ye, Chenjin Jin, Xiaoyan Li, Limin Zhao, Yuan Li, Tong Qiao

Affiliations

  1. Department of Ophthalmology, Shanghai Children's Hospital, Shanghai Jiao Tong University , Shanghai, China.
  2. State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University , Guangzhou, Guangdong Province, China.
  3. Department of Otolaryngology Head and Neck Surgery, Shanghai Children's Hospital, Shanghai Jiao Tong University , Shanghai, China.

PMID: 32730713 DOI: 10.1080/02713683.2020.1801757

Abstract

PURPOSE: Using optical coherence tomography angiography (OCT-A) to compare the retinal micro vessel alteration between obstructive sleep apnea (OSA) children and normal subjects.

METHODS: One hundred-thirty-two eyes (132 participants) were recruited in this study. The average age of OSA group (66 eyes) and healthy control group (66 eyes) were 6.23 ± 1.73 and 6.76 ± 1.89 years, respectively. The retinal vascular network density indices and the fovea avascular zone (FAZ) size were analyzed by OCT-A.

RESULTS: All of the OCT-A parafoveal vessel indices, including the vascular diameter (VD), vascular area density (VAD), vascular skeleton density (VSD), and vessel perimeter index (VPI) in the macular superficial/deep capillary plexus (SCP/DCP) as well as the FAZ in the DCP, were significantly lower in the OSA group than in the control group (

CONCLUSION: The intermittent hypoxia in children with OSA might influence the retinal capillary vascular supply. We speculate that the indices of the quadrants are lower in OSA children compared with those in healthy controls, which may be due to the change of the retinal metabolic demands. OCT-A is an ideal method to evaluate the retinal alterations in pediatric OSA.

ABBREVIATIONS: OCT-A: optical coherence tomography angiography; OSA: obstructive sleep apnea; FAZ: fovea avascular zone; VD: vascular diameter; VAD: vascular area density; VSD: vascular skeleton density; VPI: vessel perimeter index; SCP/DCP: superficial/deep capillary plexus; BCVA: best corrected visual acuity; SE: spherical equivalent; AL: ocular axial length; T: temporal; N: nasal; (S): superior; (I): inferior; (SD): standard deviation.

Keywords: Obstructive sleep apnea (OSA); children; fovea avascular zone (FAZ); optical coherence tomography angiography (OCT-A); vessel density

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