Display options
Cite
Foran P, Hwang S, Mazaheri Y, et al. High-Signal Bladder Urine at T1-Weighted MR Imaging Performed 1-7 Days After a Prior Gadolinium-Enhanced MRI: Prevalence and Correlation with Renal Function. BJR Open. 2019;1(1)doi: 10.1259/bjro.20180030.
Foran, P., Hwang, S., Mazaheri, Y., & Panicek, D. (2019). High-Signal Bladder Urine at T1-Weighted MR Imaging Performed 1-7 Days After a Prior Gadolinium-Enhanced MRI: Prevalence and Correlation with Renal Function. BJR open, 1(1), . https://doi.org/10.1259/bjro.20180030
Foran, Paul, et al. "High-Signal Bladder Urine at T1-Weighted MR Imaging Performed 1-7 Days After a Prior Gadolinium-Enhanced MRI: Prevalence and Correlation with Renal Function." BJR open vol. 1,1 (2019). doi: https://doi.org/10.1259/bjro.20180030
Foran P, Hwang S, Mazaheri Y, Panicek D. High-Signal Bladder Urine at T1-Weighted MR Imaging Performed 1-7 Days After a Prior Gadolinium-Enhanced MRI: Prevalence and Correlation with Renal Function. BJR Open. 2019;1(1). doi: 10.1259/bjro.20180030. Epub 2019 May 29. PMID: 32864561; PMCID: PMC7454119.
Copy Download .nbib Format: NLM
Share it on

BJR Open. 2019;1(1). doi: 10.1259/bjro.20180030. Epub 2019 May 29.

High-Signal Bladder Urine at T1-Weighted MR Imaging Performed 1-7 Days After a Prior Gadolinium-Enhanced MRI: Prevalence and Correlation with Renal Function.

BJR open

Paul Foran, Sinchun Hwang, Yousef Mazaheri, David Panicek

Affiliations

  1. Departments of Radiology Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  2. Medical Physics Memorial Sloan Kettering Cancer Center, New York, NY, USA.

PMID: 32864561 PMCID: PMC7454119 DOI: 10.1259/bjro.20180030

Abstract

OBJECTIVE: To determine the prevalence of high-signal bladder urine at T1-weighted MRI performed 1-7 days after injection of gadolinium-based contrast material and to assess for correlation with altered renal function.

METHODS: The study group consisted of 267 patients who underwent MRI that included the bladder 1-7 days after a prior gadolinium-enhanced MRI. A control group consisted of 200 patients who underwent pelvic MRI and had not received gadolinium-based contrast material within the prior month. One reader recorded the relative T1-weighted signal intensity of bladder urine and calculated the eGFR for each patient. A positive scan was defined as one with bladder urine T1-weighted signal higher than that of muscle.

RESULTS: Twenty-five (9%) of 267 study group scans were positive; this included 68% (n=19) of scans obtained 12-24 hours after gadolinium-based contrast material administration, 21% (n=3) after 25-36 hours, 7% (n=2) after 37-48 hours, and 3% (n=1) after 49-72 hours. No positive scan occurred after 72 hours or in the control group. Mean eGFR in positive scans obtained more than 36 hours after gadolinium-based contrast material administration was significantly lower than in negative scans in the same timeframe (37 ml/min versus 76 ml/min, respectively; p = 0.01).

CONCLUSION: High T1-weighted signal in bladder urine occasionally is present on MRI performed up to 3 days after gadolinium-based contrast material administration, presumably reflecting residual excreted gadolinium-based contrast material. When visible more than 36 hours after gadolinium-based contrast material administration, such increased signal is associated with decreased eGFR.

ADVANCES IN KNOWLEDGE: Increased signal is occasionally present on bladder urine MRI performed up to 3 days post gadolinium-based contrast material administration. When higher signal is visible more than 36 hours after gadolinium-based contrast material administration it is associated with decreased eGFR.

Conflict of interest statement

Disclosures and Conflict of Interest: None

References

  1. Invest Radiol. 2016 Feb;51(2):73-82 - PubMed
  2. Radiology. 2014 Mar;270(3):834-41 - PubMed
  3. Invest Radiol. 2015 Aug;50(8):473-80 - PubMed
  4. Invest Radiol. 2000 Jan;35(1):35-40 - PubMed
  5. Clin Imaging. 2011 May-Jun;35(3):203-7 - PubMed
  6. Invest Radiol. 1992 Aug;27 Suppl 1:S12-5 - PubMed
  7. Am J Kidney Dis. 2010 Feb;55(2):399-409 - PubMed
  8. Nephrol Dial Transplant. 2010 Feb;25(2):449-57 - PubMed
  9. J Magn Reson Imaging. 2009 Dec;30(6):1259-67 - PubMed
  10. Invest Radiol. 1993 Mar;28 Suppl 1:S44-8 - PubMed
  11. Ann Intern Med. 2009 May 5;150(9):604-12 - PubMed
  12. Jpn J Radiol. 2012 Nov;30(9):713-20 - PubMed
  13. Invest Radiol. 1991 Nov;26(11):980-6 - PubMed
  14. Acad Radiol. 1998 Jul;5(7):491-502 - PubMed
  15. Invest Radiol. 1991 Nov;26(11):975-9 - PubMed
  16. Physiol Chem Phys Med NMR. 1984;16(2):167-72 - PubMed
  17. Invest Radiol. 2006 Mar;41(3):272-8 - PubMed

Publication Types

Grant support