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Showing 1 to 12 of 2739 entries
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Venous thromboembolism after radical cystectomy: Experience with screening ultrasonography.

Arab journal of urology

Murray KM, Parker W, Stephany H, Redger K, Mirza M, Lopez-Corona E, Holzbeierlein JM, Lee EK.
PMID: 26966592
Arab J Urol. 2016 Mar;14(1):37-43. doi: 10.1016/j.aju.2015.11.002. Epub 2015 Dec 29.

OBJECTIVES: To detect the incidence of immediate postoperative deep vein thrombosis (DVT) using screening lower extremity ultrasonography (US) in patients undergoing radical cystectomy (RC) and to determine the rate of symptomatic pulmonary embolism (PE) after RC and identify risk...

The Coags Uncomplicated App: Fulfilling Educational Gaps Around Diagnosis and Laboratory Testing of Coagulation Disorders.

JMIR medical education

Kessler C, Peerschke EI, Chitlur MB, Kulkarni R, Holot N, Cooper DL.
PMID: 28420603
JMIR Med Educ. 2017 Apr 18;3(1):e6. doi: 10.2196/mededu.6858.

BACKGROUND: Patients with coagulation disorders may present to a variety of physician specialties; however, accurate and efficient diagnosis can be challenging for physicians not specialized in hematology, due to identified gaps in knowledge around appropriate laboratory assays and interpretation...

Laparoscopic retrosternal gastric pull-up for fistulized mediastinal mass.

World journal of gastrointestinal surgery

Mungo B, Barbetta A, Lidor AO, Stem M, Molena D.
PMID: 28396722
World J Gastrointest Surg. 2017 Mar 27;9(3):92-96. doi: 10.4240/wjgs.v9.i3.92.

We describe the case of a patient successfully reconstructed with laparoscopic retrosternal gastric pull-up after esophagectomy for unresectable posterior mediastinal inflammatory myofibroblastic tumor, eroding into the esophagus and compressing the airways. A partial esophagectomy with esophagostomy was performed for...

5-(Methylthio)tetrazoles as Versatile Synthons in the Stereoselective Synthesis of Polycyclic Pyrazolines via Photoinduced Intramolecular Nitrile Imine-Alkene 1,3-Dipolar Cycloaddition.

Chemical science

Pla D, Tan DS, Gin DY.
PMID: 25114776
Chem Sci. 2014 Jun 01;5(6):2407-2415. doi: 10.1039/C4SC00107A.

A key thioether substituent in readily accessible 2-alkyl-5-(methylthio)tetrazoles enables facile photoinduced denitrogenation and intramolecular nitrile imine 1,3-dipolar cycloaddition to afford a wide range of polycyclic pyrazoline products with excellent diastereoselectivity. The methylthio group red-shifts the UV absorbance of the...

TNFRSF10C copy number variation is associated with metastatic colorectal cancer.

Journal of gastrointestinal oncology

Tanenbaum DG, Hall WA, Colbert LE, Bastien AJ, Brat DJ, Kong J, Kim S, Dwivedi B, Kowalski J, Landry JC, Yu DS.
PMID: 27284460
J Gastrointest Oncol. 2016 Jun;7(3):306-14. doi: 10.21037/jgo.2015.11.04.

BACKGROUND: Genetic markers for distant metastatic disease in patients with colorectal cancer (CRC) are not well defined. Identification of genetic alterations associated with metastatic CRC could help to guide systemic and local treatment strategies. We evaluated the association of...

Id Proteins Contribute to Tumor Development and Metastatic Colonization in a Model of Bladder Carcinogenesis.

Bladder cancer (Amsterdam, Netherlands)

Garcia-Cao M, Al-Ahmadie HA, Chin Y, Bochner BH, Benezra R.
PMID: 27376116
Bladder Cancer. 2015 Oct 26;1(2):159-170. doi: 10.3233/BLC-150023.

No abstract available.

Adolescent egocentrism and indoor tanning: is the relationship direct or mediated?.

Journal of youth studies

Banerjee SC, Greene K, Yanovitzky I, Bagdasarov Z, Choi SY, Magsamen-Conrad K.
PMID: 28042281
J Youth Stud. 2015;18(3):357-375. doi: 10.1080/13676261.2014.963536. Epub 2014 Oct 10.

This paper explored how imaginary audience and personal fable ideations contribute to adolescent indoor tanning intentions directly and indirectly through the way they shape pro-tanning attitude and association with peers who use tanning beds. Five hundred and ninety-five male...

Inhibition of colorectal cancer genomic copy number alterations and chromosomal fragile site tumor suppressor FHIT and WWOX deletions by DNA mismatch repair.

Oncotarget

Jahid S, Sun J, Gelincik O, Blecua P, Edelmann W, Kucherlapati R, Zhou K, Jasin M, Gümüş ZH, Lipkin SM.
PMID: 29069730
Oncotarget. 2017 May 10;8(42):71574-71586. doi: 10.18632/oncotarget.17776. eCollection 2017 Sep 22.

Homologous recombination (HR) enables precise DNA repair after DNA double strand breaks (DSBs) using identical sequence templates, whereas homeologous recombination (HeR) uses only partially homologous sequences. Homeologous recombination introduces mutations through gene conversion and genomic deletions through single-strand annealing...

Inhibition of mTORC1/C2 signaling improves anti-leukemia efficacy of JAK/STAT blockade in .

Oncotarget

Zhang Q, Shi C, Han L, Jain N, Roberts KG, Ma H, Cai T, Cavazos A, Tabe Y, Jacamo RO, Mu H, Zhao Y, Wang J, Wu SC, Cao F, Zeng Z, Zhou J, Mi Y, Jabbour EJ, Levine R, Tasian SK, Mullighan CG, Weinstock DM, Fruman DA, Konopleva M.
PMID: 29487712
Oncotarget. 2018 Jan 17;9(8):8027-8041. doi: 10.18632/oncotarget.24261. eCollection 2018 Jan 30.

Patients with cytokine receptor-like factor 2 rearranged (

Pan-Cancer Analysis of Mutation Hotspots in Protein Domains.

Cell systems

Miller ML, Reznik E, Gauthier NP, Aksoy BA, Korkut A, Gao J, Ciriello G, Schultz N, Sander C.
PMID: 27135912
Cell Syst. 2015 Sep 23;1(3):197-209. doi: 10.1016/j.cels.2015.08.014. Epub 2015 Sep 23.

In cancer genomics, recurrence of mutations in independent tumor samples is a strong indicator of functional impact. However, rare functional mutations can escape detection by recurrence analysis owing to lack of statistical power. We enhance statistical power by extending...

Oncotarget

Pankov D, Sjöström L, Kalidindi T, Lee SG, Sjöström K, Gardner R, McDevitt MR, O'Reilly R, Thorek DLJ, Larson SM, Veach D, Ulmert D.
PMID: 29029482
Oncotarget. 2017 Jul 26;8(39):65917-65931. doi: 10.18632/oncotarget.19579. eCollection 2017 Sep 12.

Preferentially Expressed Antigen in Melanoma (PRAME) is a cancer/testis antigen that is overexpressed in a broad range of malignancies, while absent in most healthy human tissues, making it an attractive diagnostic cancer biomarker and therapeutic target. Although commonly viewed...

Phase I Designs that Allow for Uncertainty in the Attribution of Adverse Events.

Journal of the Royal Statistical Society. Series C, Applied statistics

Iasonos A, O'Quigley J.
PMID: 29085158
J R Stat Soc Ser C Appl Stat. 2017 Nov;66(5):1015-1030. doi: 10.1111/rssc.12195. Epub 2016 Nov 07.

In determining dose limiting toxicities in Phase I studies, it is necessary to attribute adverse events (AE) to being drug related or not. Such determination is subjective and may introduce bias. In this paper, we develop methods for removing...

Showing 1 to 12 of 2739 entries