Display options
Cite
Duckworth L, Black LV, Ezmigna D, et al. Spirometry use in Patients with Sickle Cell Disease with and without asthma and acute chest syndrome: A Multicenter Study. EJHaem. 2020;1(1):239-242doi: 10.1002/jha2.42.
Duckworth, L., Black, L. V., Ezmigna, D., Green, J., Yao, Y., Grannis, S., Klann, J., Applegate, R., Lipori, G., Wallace, T., & Wilkie, D. J. (2020). Spirometry use in Patients with Sickle Cell Disease with and without asthma and acute chest syndrome: A Multicenter Study. EJHaem, 1(1), 239-242. https://doi.org/10.1002/jha2.42
Duckworth, Laurie, et al. "Spirometry use in Patients with Sickle Cell Disease with and without asthma and acute chest syndrome: A Multicenter Study." EJHaem vol. 1,1 (2020): 239-242. doi: https://doi.org/10.1002/jha2.42
Duckworth L, Black LV, Ezmigna D, Green J, Yao Y, Grannis S, Klann J, Applegate R, Lipori G, Wallace T, Wilkie DJ. Spirometry use in Patients with Sickle Cell Disease with and without asthma and acute chest syndrome: A Multicenter Study. EJHaem. 2020 Jul;1(1):239-242. doi: 10.1002/jha2.42. Epub 2020 Jul 10. PMID: 32924025; PMCID: PMC7480828.
Copy Download .nbib Format: NLM
Share it on

EJHaem. 2020 Jul;1(1):239-242. doi: 10.1002/jha2.42. Epub 2020 Jul 10.

Spirometry use in Patients with Sickle Cell Disease with and without asthma and acute chest syndrome: A Multicenter Study.

EJHaem

Laurie Duckworth, L Vandy Black, Dima Ezmigna, Jeanette Green, Yingwei Yao, Shaun Grannis, Jeff Klann, Reuben Applegate, Gigi Lipori, Tanya Wallace, Diana J Wilkie

Affiliations

  1. College of Nursing, UF Health, University of Florida, Gainesville, FL.
  2. Division of Pediatric Hematology and Oncology, University of Florida College of Medicine.
  3. Division of Pulmonology, UF Health.
  4. Biobehavioral Nursing Science, AdventHealth.
  5. Biobehavioral Nursing Science, University of Florida College of Nursing.
  6. Indiana University School of Medicine.
  7. Harvard Medicine, Massachusetts General Hospital.
  8. University of Texas Health Science Center at Houston, Research.
  9. UF Health Shands, VP Information Services.
  10. College of Nursing, University of Florida.

PMID: 32924025 PMCID: PMC7480828 DOI: 10.1002/jha2.42

Abstract

A de-identified data repository of electronic medical record (EMR) data, i2b2 (Informatics for Integrating Biology and the Bedside), including 4 geographically diverse academic medical centers, was queried to determine the use of diagnostic spirometry testing in African American children and young adults 5-34 years old with sickle cell disease (SCD) with or without a documented history of asthma and/or acute chest syndrome (ACS). A total of 2,749 patients were identified with SCD, of these 577 had asthma and 409 had ACS. Cross-referencing the CPT code for diagnostic spirometry showed that for patients identified as having SCD, a history or ACS, and a diagnosis of asthma, only 31% across all 4 centers had spirometry. Having an asthma diagnosis was associated with ACS. Among SCD patients with asthma, the proportion with ACS for the four centers was 47%, 75%, 38%, and 36% respectively. The bivariate association between asthma and ACS for each Center was significant for each (p<.001). To summarize, only one third of patients with co-morbid SCD, ACS, and asthma received the spirometry procedure as recommended in evidence-based guidelines, suggesting limited testing for changes in pulmonary function. Future studies to determine barriers and facilitators to implementation of pulmonary testing in SCD are warranted.

Conflict of interest statement

Conflicts of Interest Disclosure: The authors declare no competing financial interests.

References

  1. N Engl J Med. 2000 Jun 22;342(25):1855-65 - PubMed
  2. Pediatr Allergy Immunol Pulmonol. 2017 Dec 1;30(4):191-201 - PubMed
  3. Lancet. 2016 Jun 18;387(10037):2545-53 - PubMed
  4. J Allergy Clin Immunol. 2007 Nov;120(5 Suppl):S94-138 - PubMed
  5. Ann Am Thorac Soc. 2019 Sep;16(9):e17-e32 - PubMed
  6. Blood. 2004 Jun 1;103(11):4023-7 - PubMed
  7. Haematologica. 2007 Aug;92(8):1115-8 - PubMed
  8. J Am Med Inform Assoc. 2016 Sep;23(5):909-15 - PubMed
  9. Pediatrics. 1989 Sep;84(3):500-8 - PubMed
  10. Blood Adv. 2019 Dec 10;3(23):3867-3897 - PubMed
  11. Pediatr Pulmonol. 2007 Apr;42(4):332-8 - PubMed

Publication Types

Grant support