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Showing 1 to 12 of 232 entries
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Carbon dioxide insufflation is associated with increased serrated polyp detection rate when compared to room air insufflation during screening colonoscopy.

Endoscopy international open

Riverso M, Perbtani YB, Shuster JJD, Chakraborty J, Brar TS, Agarwal M, Zhang H, Gupte A, Chauhan SS, Forsmark CE, Draganov PV, Yang D.
PMID: 28924598
Endosc Int Open. 2017 Sep;5(9):E905-E912. doi: 10.1055/s-0043-116382. Epub 2017 Sep 13.

BACKGROUND AND STUDY AIMS : Sessile serrated adenomas (SSA) and traditional serrated adenomas (TSA) have been increasingly recognized as precursors of colorectal cancer. The aim of this study was to compare the effect of carbon dioxide insufflation (CO PATIENTS...

Exploring Heteroaryl-pyrazole Carboxylic Acids as Human Carbonic Anhydrase XII Inhibitors.

ACS medicinal chemistry letters

Cadoni R, Pala N, Lomelino C, Mahon BP, McKenna R, Dallocchio R, Dessì A, Carcelli M, Rogolino D, Sanna V, Rassu M, Iaccarino C, Vullo D, Supuran CT, Sechi M.
PMID: 28947941
ACS Med Chem Lett. 2017 Jul 31;8(9):941-946. doi: 10.1021/acsmedchemlett.7b00229. eCollection 2017 Sep 14.

We report the synthesis, biological evaluation, and structural study of a series of substituted heteroaryl-pyrazole carboxylic acid derivatives. These compounds have been developed as inhibitors of specific isoforms of carbonic anhydrase (CA), with potential as prototypes of a new...

The Promise and Challenge of Induced Pluripotent Stem Cells for Cardiovascular Applications.

JACC. Basic to translational science

Youssef AA, Ross EG, Bolli R, Pepine CJ, Leeper NJ, Yang PC.
PMID: 28580434
JACC Basic Transl Sci. 2016 Oct;1(6):510-523. doi: 10.1016/j.jacbts.2016.06.010.

The recent discovery of human-induced pluripotent stem cells (iPSCs) has revolutionized the field of stem cells. iPSCs have demonstrated that biological development is not an irreversible process and that mature adult somatic cells can be induced to become pluripotent....

SegAuth: A Segment-based Approach to Behavioral Biometric Authentication.

... IEEE Conference on Communications and Network Security. IEEE Conference on Communications and Network Security

Li Y, Xie M, Bian J.
PMID: 28573214
IEEE Conf Commun Netw Secur. 2016 Oct;2016:1-9. doi: 10.1109/CNS.2016.7860464. Epub 2017 Feb 23.

Many studies have been conducted to apply behavioral biometric authentication on/with mobile devices and they have shown promising results. However, the concern about the verification accuracy of behavioral biometrics is still common given the dynamic nature of behavioral biometrics....

Mobile Device Accuracy for Step Counting Across Age Groups.

JMIR mHealth and uHealth

Modave F, Guo Y, Bian J, Gurka MJ, Parish A, Smith MD, Lee AM, Buford TW.
PMID: 28659255
JMIR Mhealth Uhealth. 2017 Jun 28;5(6):e88. doi: 10.2196/mhealth.7870.

BACKGROUND: Only one in five American meets the physical activity recommendations of the Department of Health and Human Services. The proliferation of wearable devices and smartphones for physical activity tracking has led to an increasing number of interventions designed...

Expansion of B-1a Cells with Germline Heavy Chain Sequence in Lupus Mice.

Frontiers in immunology

Holodick NE, Zeumer L, Rothstein TL, Morel L.
PMID: 27047495
Front Immunol. 2016 Mar 24;7:108. doi: 10.3389/fimmu.2016.00108. eCollection 2016.

B6.Sle1.Sle2.Sle3 (B6.TC) lupus-prone mice carrying the NZB allele of Cdkn2c, encoding for the cyclin-dependent kinase inhibitor P18(INK4), accumulate B-1a cells due to a higher rate of proliferative self-renewal. However, it is unclear whether this affects primarily early-appearing B-1a cells...

Short-Term Vitamin B-6 Restriction Does Not Affect Plasma Concentrations of Hydrogen Sulfide Biomarkers Lanthionine and Homolanthionine in Healthy Men and Women.

The Journal of nutrition

DeRatt BN, Ralat MA, Gregory JF.
PMID: 26962179
J Nutr. 2015 Apr 01;146(4):714-719. doi: 10.3945/jn.115.227819.

BACKGROUND: Suboptimal vitamin B-6 status is associated with increased cardiovascular disease risk, although the mechanism is unknown. The synthesis of the vasodilator hydrogen sulfide occurs through side reactions of the transsulfuration enzymes cystathionine β-synthase and cystathionine γ-lyase, with pyridoxal...

Characterization of Vitreous and Aqueous Proteome in Humans With Proliferative Diabetic Retinopathy and Its Clinical Correlation.

Proteomics insights

Balaiya S, Zhou Z, Chalam KV.
PMID: 28469465
Proteomics Insights. 2017 Mar 15;8:1178641816686078. doi: 10.1177/1178641816686078. eCollection 2017.

AIMS: Proliferative diabetic retinopathy (PDR) is associated with microvascular complications that cause biochemical changes in the human retina and alter the proteome of vitreous humor and aqueous humor (AH).METHODS: Human vitreous humor and AH of PDR subjects were collected....

Adenovirus-Mediated Angiotensin II Type 2 Receptor Overexpression Inhibits Tumor Growth of Prostate Cancer In Vivo.

Journal of Cancer

Li J, Luo J, Gu D, Jie F, Pei N, Li A, Chen X, Zhang Y, Du H, Chen B, Gu W, Sumners C, Li H.
PMID: 26819642
J Cancer. 2016 Jan 01;7(2):184-91. doi: 10.7150/jca.12841. eCollection 2016.

The renin-angiotensin system (RAS) plays important roles in tumorigenesis and is involved with several hallmarks of cancer. Evidence shows that angiotensin II (AngII) type 1 receptor (AT1R) blockers may be associated with improved outcome in prostate cancer patients. Furthermore,...

Examining Healthcare Utilization Patterns of Elderly Middle-Aged Adults in the United States.

Proceedings of the ... International Florida AI Research Society Conference. Florida AI Research Symposium

Zayas CE, He Z, Yuan J, Maldonado-Molina M, Hogan W, Modave F, Guo Y, Bian J.
PMID: 27430035
Proc Int Fla AI Res Soc Conf. 2016 May;2016:361-366.

Elderly patients, aged 65 or older, make up 13.5% of the U.S. population, but represent 45.2% of the top 10% of healthcare utilizers, in terms of expenditures. Middle-aged Americans, aged 45 to 64 make up another 37.0% of that...

Designing a CTSA-Based Social Network Intervention to Foster Cross-Disciplinary Team Science.

Clinical and translational science

Vacca R, McCarty C, Conlon M, Nelson DR.
PMID: 25788258
Clin Transl Sci. 2015 Aug;8(4):281-9. doi: 10.1111/cts.12267. Epub 2015 Mar 19.

This paper explores the application of network intervention strategies to the problem of assembling cross-disciplinary scientific teams in academic institutions. In a project supported by the University of Florida (UF) Clinical and Translational Science Institute, we used VIVO, a...

A survey of practices for the use of electronic health records to support research recruitment.

Journal of clinical and translational science

Obeid JS, Beskow LM, Rape M, Gouripeddi R, Black RA, Cimino JJ, Embi PJ, Weng C, Marnocha R, Buse JB.
PMID: 29657859
J Clin Transl Sci. 2017 Aug;1(4):246-252. doi: 10.1017/cts.2017.301.

Electronic health records (EHRs) provide great promise for identifying cohorts and enhancing research recruitment. Such approaches are sorely needed, but there are few descriptions in the literature of prevailing practices to guide their use. A multidisciplinary workgroup was formed...

Showing 1 to 12 of 232 entries