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Kim HY, Kim HS. Sulfatase 1 mediates IL-10-induced dimethylarginine dimethylaminohydrolase-1 expression and antiproliferative effects in vascular smooth muscle cells of spontaneously hypertensive rats. Cytokine. 2020;137:155344doi: 10.1016/j.cyto.2020.155344.
Kim, H. Y., & Kim, H. S. (2021). Sulfatase 1 mediates IL-10-induced dimethylarginine dimethylaminohydrolase-1 expression and antiproliferative effects in vascular smooth muscle cells of spontaneously hypertensive rats. Cytokine, 137155344. https://doi.org/10.1016/j.cyto.2020.155344
Kim, Hye Young, and Kim, Hee Sun. "Sulfatase 1 mediates IL-10-induced dimethylarginine dimethylaminohydrolase-1 expression and antiproliferative effects in vascular smooth muscle cells of spontaneously hypertensive rats." Cytokine vol. 137 (2021): 155344. doi: https://doi.org/10.1016/j.cyto.2020.155344
Kim HY, Kim HS. Sulfatase 1 mediates IL-10-induced dimethylarginine dimethylaminohydrolase-1 expression and antiproliferative effects in vascular smooth muscle cells of spontaneously hypertensive rats. Cytokine. 2021 Jan;137:155344. doi: 10.1016/j.cyto.2020.155344. Epub 2020 Oct 28. PMID: 33128921.
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Cytokine. 2021 Jan;137:155344. doi: 10.1016/j.cyto.2020.155344. Epub 2020 Oct 28.

Sulfatase 1 mediates IL-10-induced dimethylarginine dimethylaminohydrolase-1 expression and antiproliferative effects in vascular smooth muscle cells of spontaneously hypertensive rats.

Cytokine

Hye Young Kim, Hee Sun Kim

Affiliations

  1. Department of Microbiology, College of Medicine, Yeungnam University, Daegu, Republic of Korea.
  2. Department of Microbiology, College of Medicine, Yeungnam University, Daegu, Republic of Korea. Electronic address: [email protected].

PMID: 33128921 DOI: 10.1016/j.cyto.2020.155344

Abstract

The extracellular sulfatases (exSulfs) sulfatase 1 (Sulf1) and sulfatase 2 (Sulf2) are well-known regulators of cell signaling and metabolism. In addition, exSulfs mediate the up- or downregulatory effects of cytokines on angiotensin II (Ang II)-induced expression of hypertensive mediators in vascular smooth muscle cells (VSMC) from spontaneously hypertensive rats (SHRs). Previously, we demonstrated that interleukin-10 (IL-10)-induced dimethylarginine dimethylaminohydrolase-1 (DDAH-1) expression was mediated by Ang II subtype 2 receptor (AT

Copyright © 2020 Elsevier Ltd. All rights reserved.

Keywords: Ang II type 2 receptor; DDAH-1; Hypertension; IL-10; Sulfatase 1

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