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Scher N, Bauduceau O, Bollet M, et al. Stereotactic prostate focal reirradiation therapy for local recurrence: preliminary results of Hartmann Oncology Radiotherapy Group. BJR Open. 2019;1(1):20180027doi: 10.1259/bjro.20180027.
Scher, N., Bauduceau, O., Bollet, M., Lamallem, H., Charas, T., Garaud, P., Foster, D., Fawzi, M., Labidi, M., & Toledano, A. (2019). Stereotactic prostate focal reirradiation therapy for local recurrence: preliminary results of Hartmann Oncology Radiotherapy Group. BJR open, 1(1), 20180027. https://doi.org/10.1259/bjro.20180027
Scher, Nathaniel, et al. "Stereotactic prostate focal reirradiation therapy for local recurrence: preliminary results of Hartmann Oncology Radiotherapy Group." BJR open vol. 1,1 (2019): 20180027. doi: https://doi.org/10.1259/bjro.20180027
Scher N, Bauduceau O, Bollet M, Lamallem H, Charas T, Garaud P, Foster D, Fawzi M, Labidi M, Toledano A. Stereotactic prostate focal reirradiation therapy for local recurrence: preliminary results of Hartmann Oncology Radiotherapy Group. BJR Open. 2019 Jun 07;1(1):20180027. doi: 10.1259/bjro.20180027. eCollection 2019. PMID: 33178921; PMCID: PMC7592466.
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BJR Open. 2019 Jun 07;1(1):20180027. doi: 10.1259/bjro.20180027. eCollection 2019.

Stereotactic prostate focal reirradiation therapy for local recurrence: preliminary results of Hartmann Oncology Radiotherapy Group.

BJR open

Nathaniel Scher, Olivier Bauduceau, Marc Bollet, Hanah Lamallem, Tomer Charas, Pascal Garaud, Denis Foster, Maher Fawzi, Mona Labidi, Alain Toledano

Affiliations

  1. Department of Radiation Oncology, MSKCC, New York, USA.
  2. Hartmann Radiotherapy Institute, Hartmann Oncology Radiotherapy Group, Levallois-Perret, France.

PMID: 33178921 PMCID: PMC7592466 DOI: 10.1259/bjro.20180027

Abstract

OBJECTIVE: Our objective was to report our experience and to evaluate the feasibility and toxicity of focal salvage stereotactic body radiation therapy (SBRT) in patients with post-radiation local recurrence of prostate cancer.

METHODS: We retrospectively reviewed medical records of patients treated with Cyberknife

RESULTS: 42 patients were treated with followed with a median follow-up of 21 months (range 3 - 31). 34 patients had biopsy proven recurrence. The initial treatment was radical prostatectomy and radiation therapy for 9 patients and radiation therapy alone for 33 patients. 23 patients from the group of prostate reirradiation had placement of rectal spacers. No Grade 4 or 5 toxicity were observed. 27 acute urinary events were recorded: 18 patients experienced Grade 1, 9 patients experienced Grade 2 toxicity and 1 patient experienced Grade 3 urinary toxicity, namely cystitis and/or dysuria. No Grade 2 or more digestive toxicity was observed. Rectal doses were significantly lower with rectal spacers.

CONCLUSION: Salvage focal Cyberknife

ADVANCES IN KNOWLEDGE: SBRT for local prostate cancer recurrence after initial radiotherapy is well tolerated with short follow-up.

© 2019 The Authors. Published by the British Institute of Radiology.

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