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Tsilifis C, Schim van der Loeff I, Williams E, et al. BCG lymphadenitis: a potential complication of immune reconstitution following haematopoietic stem cell transplant. Arch Dis Child Educ Pract Ed. 2020;doi: 10.1136/archdischild-2020-320883.
Tsilifis, C., Schim van der Loeff, I., Williams, E., Owens, S., Powell, S., Gennery, A., & Slatter, M. (2020). BCG lymphadenitis: a potential complication of immune reconstitution following haematopoietic stem cell transplant. Archives of disease in childhood. Education and practice edition, . https://doi.org/10.1136/archdischild-2020-320883
Tsilifis, Christo, et al. "BCG lymphadenitis: a potential complication of immune reconstitution following haematopoietic stem cell transplant." Archives of disease in childhood. Education and practice edition vol. (2020). doi: https://doi.org/10.1136/archdischild-2020-320883
Tsilifis C, Schim van der Loeff I, Williams E, Owens S, Powell S, Gennery A, Slatter M. BCG lymphadenitis: a potential complication of immune reconstitution following haematopoietic stem cell transplant. Arch Dis Child Educ Pract Ed. 2020 Dec 18; doi: 10.1136/archdischild-2020-320883. Epub 2020 Dec 18. PMID: 33355234.
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Arch Dis Child Educ Pract Ed. 2020 Dec 18; doi: 10.1136/archdischild-2020-320883. Epub 2020 Dec 18.

BCG lymphadenitis: a potential complication of immune reconstitution following haematopoietic stem cell transplant.

Archives of disease in childhood. Education and practice edition

Christo Tsilifis, Ina Schim van der Loeff, Eleri Williams, Stephen Owens, Steven Powell, Andrew Gennery, Mary Slatter

Affiliations

  1. Paediatric Immunology and Infectious Diseases, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK [email protected].
  2. Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, Tyne and Wear, UK.
  3. Paediatric Immunology and Infectious Diseases, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
  4. Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.
  5. Paediatric Otolaryngology, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
  6. Paediatric Haematopoietic Stem Cell Transplant Unit, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.

PMID: 33355234 DOI: 10.1136/archdischild-2020-320883

Abstract

Case reportAn MHC class II deficient 2-year-old boy presented with fever and an enlarging left neck mass 100 days post allogeneic haematopoietic stem cell transplant (HSCT). Fever persisted despite treatment with broad-spectrum β-lactam antibiotics. His BCG vaccination site at presentation was quiescent. Ultrasound showed enlarged cervical lymph nodes. An incisional biopsy of the large nodal mass yielded acid-fast bacilli, identified as

© Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ.

Keywords: HIV; cell biology; genetics; pathology; syndrome

Conflict of interest statement

Competing interests: None declared.

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