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Front Physiol. 2020 Nov 19;11:613948. doi: 10.3389/fphys.2020.613948. eCollection 2020.

Current Perspectives on Characteristics, Compositions, and Toxicological Effects of E-Cigarettes Containing Tobacco and Menthol/Mint Flavors.

Frontiers in physiology

Gurjot Kaur, Anshuman Gaurav, Thomas Lamb, Melanie Perkins, Thivanka Muthumalage, Irfan Rahman

Affiliations

  1. School of Pharmaceutical Sciences, Shoolini University, Solan, India.
  2. Department of Environmental Medicine, University of Rochester Medical Center, Rochester, NY, United States.

PMID: 33329065 PMCID: PMC7710937 DOI: 10.3389/fphys.2020.613948

Abstract

Electronic nicotine delivery systems/devices (ENDS) such as electronic cigarettes (e-cigarettes) have been made available globally, with the intent to reduce tobacco smoking. To make these products more appealing to young adults, many brands have added flavoring agents. However, these flavoring agents are shown to progressively result in lung toxicity when inhaled via e-cigarettes. While recent federal regulations have banned the sale of flavored e-cigarettes other than tobacco or menthol flavors, concerns have been raised about the health effects of even these flavors. In this review, we evaluate the current toxicological data with regard to effects upon exposure in animal models and

Copyright © 2020 Kaur, Gaurav, Lamb, Perkins, Muthumalage and Rahman.

Keywords: e-cigarettes; menthol; mint; tobacco; toxicity

References

  1. J Am Heart Assoc. 2017 Sep 20;6(9): - PubMed
  2. iScience. 2019 Jun 28;16:250-269 - PubMed
  3. Arterioscler Thromb Vasc Biol. 2018 Jul;38(7):1607-1615 - PubMed
  4. Am J Respir Cell Mol Biol. 2018 Mar;58(3):366-377 - PubMed
  5. Prev Med. 2017 Jan;94:65-71 - PubMed
  6. PLoS One. 2018 Aug 23;13(8):e0202744 - PubMed
  7. Toxicol Lett. 2018 May 15;288:143-155 - PubMed
  8. Tob Control. 2016 Nov;25(Suppl 2):ii81-ii87 - PubMed
  9. Toxics. 2020 Apr 03;8(2): - PubMed
  10. Chest. 2012 Jun;141(6):1400-1406 - PubMed
  11. Am J Respir Cell Mol Biol. 2020 Sep;63(3):306-316 - PubMed
  12. Front Physiol. 2020 Sep 04;11:924 - PubMed
  13. Toxics. 2020 Jun 28;8(3): - PubMed
  14. JAMA Intern Med. 2019 Sep 16;: - PubMed
  15. Proc Natl Acad Sci U S A. 2019 Oct 22;116(43):21727-21731 - PubMed
  16. Nicotine Tob Res. 2010 Dec;12 Suppl 2:S110-6 - PubMed
  17. Front Endocrinol (Lausanne). 2019 Jun 04;10:320 - PubMed
  18. Am J Physiol Lung Cell Mol Physiol. 2017 Jul 1;313(1):L52-L66 - PubMed
  19. Ann Plast Surg. 2017 Jul;79(1):86-91 - PubMed
  20. Am J Public Health. 2020 Jun;110(6):785-787 - PubMed
  21. Sci Rep. 2020 Feb 13;10(1):2544 - PubMed
  22. J Cardiovasc Pharmacol Ther. 2020 Nov;25(6):578-586 - PubMed
  23. BMC Public Health. 2017 Dec 29;17(1):983 - PubMed
  24. Prev Med. 2020 Jan;130:105898 - PubMed
  25. Tob Control. 2018 May 28;: - PubMed
  26. Biochem Biophys Res Commun. 2016 Sep 2;477(4):620-625 - PubMed
  27. Chemosphere. 2020 Jun;249:126153 - PubMed
  28. Int J Environ Res Public Health. 2016 Apr 12;13(4):417 - PubMed
  29. PLoS One. 2015 Feb 04;10(2):e0116861 - PubMed
  30. Am J Respir Cell Mol Biol. 2020 Dec;63(6):794-805 - PubMed
  31. Ann Am Thorac Soc. 2020 May;17(5):573-581 - PubMed
  32. PLoS One. 2014 Sep 22;9(9):e108342 - PubMed
  33. Chem Res Toxicol. 2003 Aug;16(8):988-93 - PubMed
  34. Head Face Med. 2014 Sep 15;10:39 - PubMed
  35. Toxicol Sci. 2018 Mar 1;162(1):276-286 - PubMed
  36. Front Physiol. 2018 Jan 11;8:1130 - PubMed
  37. Oral Oncol. 2016 Jan;52:58-65 - PubMed
  38. Curr Cardiol Rep. 2019 Aug 28;21(10):111 - PubMed
  39. Am J Physiol Lung Cell Mol Physiol. 2018 Nov 1;315(5):L662-L672 - PubMed
  40. Chin J Physiol. 2018 Mar 12;61(2):75-84 - PubMed
  41. Sci Rep. 2019 Feb 21;9(1):2468 - PubMed
  42. Toxicol Mech Methods. 2016 Jul;26(6):427-34 - PubMed
  43. Toxicol Lett. 2020 Oct 15;333:303-311 - PubMed
  44. Nicotine Tob Res. 2015 Oct;17(10):1286-7 - PubMed
  45. Inhal Toxicol. 2017 Feb;29(3):126-136 - PubMed
  46. Prev Chronic Dis. 2018 Aug 23;15:E105 - PubMed
  47. Eur Respir J. 2018 Feb 7;51(2): - PubMed
  48. Tob Control. 2018 May;27(3):325-333 - PubMed
  49. J Am Heart Assoc. 2018 Jul 18;7(15): - PubMed
  50. J Hypertens. 2019 Jan;37(1):154-166 - PubMed
  51. Toxicol Mech Methods. 2016 Jul;26(6):419-26 - PubMed
  52. Toxicol Sci. 2019 Aug 28;: - PubMed
  53. Int J Environ Res Public Health. 2017 Oct 20;14(10): - PubMed
  54. MMWR Morb Mortal Wkly Rep. 2018 Nov 16;67(45):1276-1277 - PubMed
  55. JAMA. 2014 Dec 17;312(23):2493-4 - PubMed
  56. JAMA. 2019 Nov 5;: - PubMed
  57. Am J Physiol Lung Cell Mol Physiol. 2017 Jul 1;313(1):L67-L79 - PubMed
  58. J Appl Toxicol. 2019 Jun;39(6):888-898 - PubMed
  59. Am J Physiol Lung Cell Mol Physiol. 2020 Oct 1;319(4):L717-L727 - PubMed
  60. Tob Control. 2015 Jan;24(1):28-37 - PubMed
  61. PLoS One. 2015 Feb 06;10(2):e0116732 - PubMed
  62. Harm Reduct J. 2018 Jun 28;15(1):33 - PubMed
  63. Ann N Y Acad Sci. 2019 Sep;1452(1):65-77 - PubMed
  64. Prev Med Rep. 2016 Nov 11;5:33-40 - PubMed
  65. Drug Alcohol Depend. 2017 Nov 1;180:193-199 - PubMed
  66. Oncotarget. 2016 Nov 22;7(47):77196-77204 - PubMed
  67. PLoS One. 2016 Jun 28;11(6):e0157337 - PubMed

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