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Zambarbieri J, Tagliasacchi F, Moretti P, et al. Analytical and Clinical Validation of a New Immunoenzymatic Method for the Measurement of Canine Parathyroid Hormone. Animals (Basel). 2020;10(12)doi: 10.3390/ani10122411.
Zambarbieri, J., Tagliasacchi, F., Moretti, P., Giordano, A., & Scarpa, P. (2020). Analytical and Clinical Validation of a New Immunoenzymatic Method for the Measurement of Canine Parathyroid Hormone. Animals : an open access journal from MDPI, 10(12), . https://doi.org/10.3390/ani10122411
Zambarbieri, Jari, et al. "Analytical and Clinical Validation of a New Immunoenzymatic Method for the Measurement of Canine Parathyroid Hormone." Animals : an open access journal from MDPI vol. 10,12 (2020). doi: https://doi.org/10.3390/ani10122411
Zambarbieri J, Tagliasacchi F, Moretti P, Giordano A, Scarpa P. Analytical and Clinical Validation of a New Immunoenzymatic Method for the Measurement of Canine Parathyroid Hormone. Animals (Basel). 2020 Dec 17;10(12). doi: 10.3390/ani10122411. PMID: 33348538; PMCID: PMC7766972.
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Animals (Basel). 2020 Dec 17;10(12). doi: 10.3390/ani10122411.

Analytical and Clinical Validation of a New Immunoenzymatic Method for the Measurement of Canine Parathyroid Hormone.

Animals : an open access journal from MDPI

Jari Zambarbieri, Filippo Tagliasacchi, Pierangelo Moretti, Alessia Giordano, Paola Scarpa

Affiliations

  1. Department of Veterinary Medicine, University of Milan, Via dell'Università 6, 26900 Lodi, Italy.

PMID: 33348538 PMCID: PMC7766972 DOI: 10.3390/ani10122411

Abstract

Renal hyperparathyroidism (RHPT) is one of the main complications in dogs affected with Chronic Kidney Disease (CKD). The measurement of serum parathyroid hormone (PTH) could be of clinical utility for the disease's treatment and follow-up; however, PTH is not routinely determined due to limited available methods, often not fully validated in dogs. The aims of this study were the analytical validation of an immunoenzymatic method for the measurement of PTH in canine serum and the analysis of preliminary association of the obtained results with renal function. Twenty-six samples obtained from dogs healthy or affected with CKD were analysed. PTH was measured using a two-site immunoenzymometric human assay (ST AIA-PACK

Keywords: biological marker; chronic kidney disease; dog; method validation; parathyroid hormone; renal hyperparathyroidism

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