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Can J Infect Dis Med Microbiol. 2021 Feb 18;2021:8838444. doi: 10.1155/2021/8838444. eCollection 2021.

Effect of Antifungal-Treated Host Macrophages on .

The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale

Hong-Bin Li, Na Li, Shu-Ran Wen, Ming-Yue Qiang, Zheng-Hui Yang, Tian-Xiang Dong, Yu-Ye Li, Yi-Qun Kuang

Affiliations

  1. Department of Dermatology and Venereology, First Affiliated Hospital of Kunming Medical University, Kunming 650032, Yunnan, China.
  2. NHC Key Laboratory of Drug Addiction Medicine, First Affiliated Hospital of Kunming Medical University, Kunming Medical University, Kunming 650032, Yunnan, China.
  3. Scientific Research Laboratory Center, First Affiliated Hospital of Kunming Medical University, Kunming 650032, Yunnan, China.

PMID: 33680221 PMCID: PMC7906804 DOI: 10.1155/2021/8838444

Abstract

METHODS: RAW264.1 macrophages were treated with MCF, ICZ, or AmB and then challenged with

RESULTS: The activity of SOD was significantly increased in RAW264.1 cells that phagocytized

CONCLUSION: Echinocandins may increase their antifungal efficacy by altering the innate immune response of macrophages and attenuating antioxidants of this organism.

Copyright © 2021 Hong-Bin Li et al.

Conflict of interest statement

The authors declare that they have no conflicts of interest.

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