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Scopetti D, Piobbico D, Brunacci C, et al. INSL4 as prognostic marker for proliferation and invasiveness in Non-Small-Cell Lung Cancer. J Cancer. 2021;12(13):3781-3795doi: 10.7150/jca.51332.
Scopetti, D., Piobbico, D., Brunacci, C., Pieroni, S., Bellezza, G., Castelli, M., Ludovini, V., Tofanetti, F. R., Cagini, L., Sidoni, A., Puxeddu, E., Della-Fazia, M. A., & Servillo, G. (2021). INSL4 as prognostic marker for proliferation and invasiveness in Non-Small-Cell Lung Cancer. Journal of Cancer, 12(13), 3781-3795. https://doi.org/10.7150/jca.51332
Scopetti, Damiano, et al. "INSL4 as prognostic marker for proliferation and invasiveness in Non-Small-Cell Lung Cancer." Journal of Cancer vol. 12,13 (2021): 3781-3795. doi: https://doi.org/10.7150/jca.51332
Scopetti D, Piobbico D, Brunacci C, Pieroni S, Bellezza G, Castelli M, Ludovini V, Tofanetti FR, Cagini L, Sidoni A, Puxeddu E, Della-Fazia MA, Servillo G. INSL4 as prognostic marker for proliferation and invasiveness in Non-Small-Cell Lung Cancer. J Cancer. 2021 May 05;12(13):3781-3795. doi: 10.7150/jca.51332. eCollection 2021. PMID: 34093787; PMCID: PMC8176261.
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J Cancer. 2021 May 05;12(13):3781-3795. doi: 10.7150/jca.51332. eCollection 2021.

INSL4 as prognostic marker for proliferation and invasiveness in Non-Small-Cell Lung Cancer.

Journal of Cancer

Damiano Scopetti, Danilo Piobbico, Cinzia Brunacci, Stefania Pieroni, Guido Bellezza, Marilena Castelli, Vienna Ludovini, Francesca Romana Tofanetti, Lucio Cagini, Angelo Sidoni, Efisio Puxeddu, Maria Agnese Della-Fazia, Giuseppe Servillo

Affiliations

  1. Department of Medicine and Surgery, Section of General Pathology, University of Perugia, Perugia- Italy.
  2. Department of Medicine and Surgery, Section of Anatomic Pathology and Histology, University of Perugia, Perugia- Italy.
  3. Medical Oncology, S. Maria Della Misericordia Hospital, Perugia, Italy.
  4. Department of Medicine and Surgery, Section of internal medicine, angiology and atherosclerosis diseases.
  5. Department of Medicine and Surgery, Section of internal medicine and endocrine and metabolic sciences.

PMID: 34093787 PMCID: PMC8176261 DOI: 10.7150/jca.51332

Abstract

Non-small-cell-lung cancer accounts for 80-85% of all forms of lung cancer as leading cause of cancer-related death in human. Despite remarkable advances in the diagnosis and therapy of lung cancer, no significant improvements have thus far been achieved in terms of patients' prognosis. Here, we investigated the role of INSL4 - a member of the relaxin-family - in NSCLC. We overexpressed INSL4 in NSCLC cells to analyse

© The author(s).

Keywords: INSL4; NSCLC adenocarcinoma; invasiveness; proliferation; xenograft mouse

Conflict of interest statement

Competing Interests: The authors have declared that no competing interest exists.

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