Display options
Cite
Fernández-García V, González-Ramos S, Martín-Sanz P, et al. NOD1-Targeted Immunonutrition Approaches: On the Way from Disease to Health. Biomedicines. 2021;9(5)doi: 10.3390/biomedicines9050519.
Fernández-García, V., González-Ramos, S., Martín-Sanz, P., Laparra, J. M., & Boscá, L. (2021). NOD1-Targeted Immunonutrition Approaches: On the Way from Disease to Health. Biomedicines, 9(5), . https://doi.org/10.3390/biomedicines9050519
Fernández-García, Victoria, et al. "NOD1-Targeted Immunonutrition Approaches: On the Way from Disease to Health." Biomedicines vol. 9,5 (2021). doi: https://doi.org/10.3390/biomedicines9050519
Fernández-García V, González-Ramos S, Martín-Sanz P, Laparra JM, Boscá L. NOD1-Targeted Immunonutrition Approaches: On the Way from Disease to Health. Biomedicines. 2021 May 06;9(5). doi: 10.3390/biomedicines9050519. PMID: 34066406; PMCID: PMC8148154.
Copy Download .nbib Format: NLM
Share it on

Biomedicines. 2021 May 06;9(5). doi: 10.3390/biomedicines9050519.

NOD1-Targeted Immunonutrition Approaches: On the Way from Disease to Health.

Biomedicines

Victoria Fernández-García, Silvia González-Ramos, Paloma Martín-Sanz, José M Laparra, Lisardo Boscá

Affiliations

  1. Instituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM), Arturo Duperier 4, 28029 Madrid, Spain.
  2. Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares (CIBERCV), Melchor Fernández Almagro 6, 28029 Madrid, Spain.
  3. Centro de Investigación Biomédica en Red en Enfermedades Hepáticas (CIBERehd), 28029 Madrid, Spain.
  4. Madrid Institute for Advanced studies in Food (IMDEA Food), Ctra. Cantoblanco 8, 28049 Madrid, Spain.

PMID: 34066406 PMCID: PMC8148154 DOI: 10.3390/biomedicines9050519

Abstract

Immunonutrition appears as a field with great potential in modern medicine. Since the immune system can trigger serious pathophysiological disorders, it is essential to study and implement a type of nutrition aimed at improving immune system functioning and reinforcing it individually for each patient. In this sense, the nucleotide-binding oligomerization domain-1 (NOD1), one of the members of the pattern recognition receptors (PRRs) family of innate immunity, has been related to numerous pathologies, such as cancer, diabetes, or cardiovascular diseases. NOD1, which is activated by bacterial-derived peptidoglycans, is known to be present in immune cells and to contribute to inflammation and other important pathways, such as fibrosis, upon recognition of its ligands. Since immunonutrition is a significant developing research area with much to discover, we propose NOD1 as a possible target to consider in this field. It is relevant to understand the cellular and molecular mechanisms that modulate the immune system and involve the activation of NOD1 in the context of immunonutrition and associated pathological conditions. Surgical or pharmacological treatments could clearly benefit from the synergy with specific and personalized nutrition that even considers the health status of each subject.

Keywords: NOD1; cancer; exercise; immunonutrition; lipids; microbiota; personalized medicine

References

  1. Front Cell Dev Biol. 2019 Oct 02;7:208 - PubMed
  2. Am J Physiol Endocrinol Metab. 2016 Jun 1;310(11):E982-93 - PubMed
  3. J Immunol. 2016 Jun 15;196(12):5121-9 - PubMed
  4. Apoptosis. 2015 Feb;20(2):174-95 - PubMed
  5. Placenta. 2021 Feb;105:23-31 - PubMed
  6. Kidney Dis (Basel). 2016 Apr;2(1):28-36 - PubMed
  7. Protein Cell. 2020 Mar;11(3):187-201 - PubMed
  8. Oncotarget. 2016 Sep 20;7(38):61820-61831 - PubMed
  9. Immunology. 2018 Sep;155(1):36-52 - PubMed
  10. Mucosal Immunol. 2013 Mar;6(2):235-43 - PubMed
  11. Nat Rev Immunol. 2017 Jan;17(1):21-29 - PubMed
  12. FASEB J. 2001 Dec;15(14):2555 - PubMed
  13. Endocrinology. 2019 May 1;160(5):1021-1030 - PubMed
  14. Arterioscler Thromb Vasc Biol. 2011 May;31(5):1093-9 - PubMed
  15. Inflamm Bowel Dis. 2019 Jan 10;25(2):294-305 - PubMed
  16. Int J Mol Sci. 2019 Mar 05;20(5): - PubMed
  17. Surg Clin North Am. 2003 Jun;83(3):571-96 - PubMed
  18. Am J Reprod Immunol. 2009 Apr;61(4):294-302 - PubMed
  19. Cell Death Differ. 2017 Jul;24(7):1160-1171 - PubMed
  20. Br J Nutr. 2013 Jan;109 Suppl 2:S81-5 - PubMed
  21. Diabetes. 2011 Sep;60(9):2206-15 - PubMed
  22. Cochrane Database Syst Rev. 2019 Jan 24;1:CD012041 - PubMed
  23. Gastroenterology. 2012 Oct;143(4):913-6.e7 - PubMed
  24. Nature. 2021 Mar;591(7850):371-372 - PubMed
  25. Microb Pathog. 2018 Sep;122:58-62 - PubMed
  26. Curr Gastroenterol Rep. 2002 Aug;4(4):332-7 - PubMed
  27. Oncotarget. 2019 Jan 22;10(7):760-772 - PubMed
  28. Microb Pathog. 2019 Mar;128:390-395 - PubMed
  29. J Immunol. 2011 Jul 15;187(2):980-6 - PubMed
  30. Int J Sport Nutr Exerc Metab. 2019 Mar 1;29(2):181-188 - PubMed
  31. Food Funct. 2020 Sep 23;11(9):7994-8002 - PubMed
  32. Immunol Rev. 2020 Sep;297(1):139-161 - PubMed
  33. Sci Rep. 2017 May 8;7(1):1578 - PubMed
  34. Nutr Hosp. 2015 Feb 26;31 Suppl 3:145-54 - PubMed
  35. BMJ. 2003 Jul 19;327(7407):117-8 - PubMed
  36. J Dent Res. 2010 Feb;89(2):186-91 - PubMed
  37. Sci Immunol. 2020 Sep 17;5(51): - PubMed
  38. Cell Res. 2019 Jul;29(7):516-532 - PubMed
  39. BMC Genomics. 2019 Feb 21;20(1):152 - PubMed
  40. Clin Sci (Lond). 1998 Aug;95(2):115-28 - PubMed
  41. Nature. 2018 Feb 8;554(7691):255-259 - PubMed
  42. Nat Rev Gastroenterol Hepatol. 2010 Dec;7(12):691-701 - PubMed
  43. Aging Dis. 2012 Feb;3(1):91-129 - PubMed
  44. Int J Clin Exp Pathol. 2018 Dec 01;11(12):5745-5754 - PubMed
  45. Inflamm Regen. 2017 May 3;37:9 - PubMed
  46. World J Gastroenterol. 2013 May 28;19(20):2985-96 - PubMed
  47. Nutrition. 2004 Jun;20(6):587-9 - PubMed
  48. Nutr Res. 2017 May;41:14-35 - PubMed
  49. Biomed Res Int. 2016;2016:9325436 - PubMed
  50. Br J Anaesth. 1996 Jul;77(1):118-27 - PubMed
  51. Exerc Immunol Rev. 2017;23:8-50 - PubMed
  52. Proc Natl Acad Sci U S A. 2006 Feb 7;103(6):1840-5 - PubMed
  53. Cell Rep. 2017 Mar 7;18(10):2415-2426 - PubMed
  54. Crit Care Nurs Clin North Am. 2012 Jun;24(2):179-200 - PubMed
  55. Am J Physiol Endocrinol Metab. 2011 Oct;301(4):E587-98 - PubMed
  56. Cell Biochem Funct. 2019 Oct;37(7):464-473 - PubMed
  57. J Hepatol. 2019 Jun;70(6):1159-1169 - PubMed
  58. Eur J Nutr. 2005 Jun;44 Suppl 1:i5-30 - PubMed
  59. Nature. 2016 Jul 06;535(7610):65-74 - PubMed
  60. J Clin Pharmacol. 2016 Feb;56(2):157-69 - PubMed
  61. J Immunol. 2016 Mar 15;196(6):2779-87 - PubMed
  62. Nutrients. 2020 Jun 30;12(7): - PubMed
  63. Mol Cell Endocrinol. 2021 May 25;533:111333 - PubMed
  64. Nutrients. 2013 Mar 12;5(3):829-51 - PubMed
  65. Nature. 2018 May;557(7706):595-597 - PubMed
  66. Cell Death Differ. 2007 Apr;14(4):830-9 - PubMed
  67. Curr Opin Pharmacol. 2019 Oct;48:107-113 - PubMed
  68. Eur J Clin Nutr. 2003 Sep;57 Suppl 1:S66-9 - PubMed
  69. Front Immunol. 2017 Jul 31;8:888 - PubMed
  70. Mol Oral Microbiol. 2016 Jun;31(3):243-258 - PubMed
  71. JPEN J Parenter Enteral Nutr. 2002 Jan-Feb;26(1):67-9 - PubMed
  72. Nutr Health. 1995;10(3):191-200 - PubMed
  73. Nutr Clin Pract. 2010 Feb;25(1):61-8 - PubMed
  74. Nat Rev Immunol. 2016 Apr 28;16(5):279-94 - PubMed
  75. Sci Rep. 2020 Jul 23;10(1):12317 - PubMed
  76. J Exp Med. 2012 Dec 17;209(13):2395-408 - PubMed
  77. Cell Physiol Biochem. 2015;36(2):457-73 - PubMed
  78. J Cancer Res Clin Oncol. 2019 Jun;145(6):1405-1416 - PubMed
  79. Exp Clin Endocrinol Diabetes. 2016 Sep;124(8):512-517 - PubMed
  80. Br J Nutr. 2015 Nov 14;114(9):1329-30 - PubMed
  81. Physiol Rev. 2017 Jul 1;97(3):1165-1209 - PubMed
  82. Trends Immunol. 2014 Mar;35(3):123-30 - PubMed
  83. Nephron. 2017;137(1):68-76 - PubMed
  84. Front Immunol. 2014 Jul 14;5:327 - PubMed
  85. Semin Immunopathol. 2007 Sep;29(3):289-301 - PubMed
  86. Mol Cell. 2017 Jun 15;66(6):750-760 - PubMed
  87. Front Immunol. 2019 Oct 25;10:2441 - PubMed
  88. Nature. 2011 Jun 15;474(7351):327-36 - PubMed
  89. Immunity. 2007 Apr;26(4):445-59 - PubMed
  90. Cell Rep. 2021 Jan 26;34(4):108677 - PubMed
  91. Nat Med. 2010 Feb;16(2):228-31 - PubMed
  92. Nutr Rev. 2008 Jun;66(6):310-20 - PubMed
  93. Infect Agent Cancer. 2020 Jan 30;15:6 - PubMed
  94. Cells. 2020 Sep 10;9(9): - PubMed
  95. J Endocrinol. 2014 Jul;222(1):99-112 - PubMed
  96. J Exp Med. 2017 Oct 2;214(10):3067-3083 - PubMed
  97. Cardiovasc Res. 2015 Jun 1;106(3):375-86 - PubMed
  98. Circulation. 2020 Dec 8;142(23):2240-2258 - PubMed
  99. J Biol Chem. 2020 Mar 6;295(10):3099-3114 - PubMed
  100. Eur Respir J. 2007 Aug;30(2):214-22 - PubMed
  101. Endocrine. 2019 Jun;64(3):564-574 - PubMed
  102. Blood. 2017 Jan 12;129(2):171-176 - PubMed
  103. Trends Immunol. 2017 Oct;38(10):758-767 - PubMed
  104. Front Immunol. 2020 Jan 24;10:3081 - PubMed
  105. Biol Open. 2012 Dec 15;1(12):1239-47 - PubMed
  106. PLoS Pathog. 2013 Jan;9(1):e1003152 - PubMed
  107. Cell Mol Biol Lett. 2018 May 9;23:23 - PubMed
  108. J Immunol. 2015 Jan 15;194(2):773-80 - PubMed
  109. Cent Eur J Immunol. 2015;40(3):311-24 - PubMed
  110. Nat Rev Drug Discov. 2009 Jun;8(6):465-79 - PubMed
  111. Drug Discov Today Dis Mech. 2008 Jun 1;5(2):145-152 - PubMed
  112. Diabetes Metab. 2012 Dec;38(6):538-43 - PubMed
  113. Cancer Res. 2019 Apr 1;79(7):1600-1611 - PubMed
  114. Vet Immunol Immunopathol. 2012 Nov 15;150(1-2):133-9 - PubMed
  115. Int J Mol Sci. 2021 Jan 25;22(3): - PubMed
  116. Front Immunol. 2019 Nov 19;10:2648 - PubMed
  117. J Biol Chem. 2001 Jan 26;276(4):2551-4 - PubMed
  118. Biosci Rep. 2019 Apr 9;39(4): - PubMed
  119. Immunol Cell Biol. 2000 Oct;78(5):554-61 - PubMed
  120. J Immunol. 2010 Mar 1;184(5):2297-304 - PubMed
  121. Trends Microbiol. 2013 May;21(5):221-9 - PubMed
  122. Nat Commun. 2020 Apr 24;11(1):1978 - PubMed
  123. FASEB J. 2019 Mar;33(3):3912-3921 - PubMed
  124. Front Immunol. 2020 Oct 26;11:586527 - PubMed
  125. Gastroenterology. 2017 Apr;152(5):1100-1113.e12 - PubMed

Publication Types

Grant support