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Arrizabalaga-Larrañaga A, Nielen MWF, Blokland MH. Hand-Held Diode Laser for On-Site Analysis Using Transportable Mass Spectrometry. Anal Chem. 2021;93(23):8122-8127doi: 10.1021/acs.analchem.1c01083.
Arrizabalaga-Larrañaga, A., Nielen, M. W. F., & Blokland, M. H. (2021). Hand-Held Diode Laser for On-Site Analysis Using Transportable Mass Spectrometry. Analytical chemistry, 93(23), 8122-8127. https://doi.org/10.1021/acs.analchem.1c01083
Arrizabalaga-Larrañaga, Ane, et al. "Hand-Held Diode Laser for On-Site Analysis Using Transportable Mass Spectrometry." Analytical chemistry vol. 93,23 (2021): 8122-8127. doi: https://doi.org/10.1021/acs.analchem.1c01083
Arrizabalaga-Larrañaga A, Nielen MWF, Blokland MH. Hand-Held Diode Laser for On-Site Analysis Using Transportable Mass Spectrometry. Anal Chem. 2021 Jun 15;93(23):8122-8127. doi: 10.1021/acs.analchem.1c01083. Epub 2021 Jun 02. PMID: 34077188; PMCID: PMC8253484.
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Anal Chem. 2021 Jun 15;93(23):8122-8127. doi: 10.1021/acs.analchem.1c01083. Epub 2021 Jun 02.

Hand-Held Diode Laser for On-Site Analysis Using Transportable Mass Spectrometry.

Analytical chemistry

Ane Arrizabalaga-Larrañaga, Michel W F Nielen, Marco H Blokland

Affiliations

  1. Department of Chemical Engineering and Analytical Chemistry, University of Barcelona, Av. Diagonal 645, E-08028 Barcelona, Spain.
  2. Wageningen Food Safety Research (WFSR), Wageningen University & Research, P.O. Box 230, 6700 AE Wageningen, The Netherlands.
  3. Laboratory of Organic Chemistry, Wageningen University, Stippeneng 4, 6708 WE Wageningen, The Netherlands.

PMID: 34077188 PMCID: PMC8253484 DOI: 10.1021/acs.analchem.1c01083

Abstract

A hand-held laser diode thermal desorption electrospray ionization (LDTD-ESI) mass spectrometry (MS) method was developed for rapid screening of illegal substances in solid samples. To achieve that, a simple, inexpensive, battery-powered surgical laser diode at 940 nm was employed to ablate the solid samples. The potential of using a black polytetrafluoroethylene substrate to enhance the analytes' desorption to the gas phase was investigated and demonstrated. Among the optimized ESI parameters, the solvent (methanol/water, 50:50,

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